1234799-83-7

Upstream product

• 29671-92-9 chloroformamidine hydrochloride 
• 37572-24-0 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylic acid ethyl ester 
• 14063-79-7 3-chloro-3-(4-methoxyphenyl)acrylaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 57466-68-9 3-chloro-3-(4-methoxyphenyl)acrylonitrile 

Downstream Products

• 1610730-78-3 4-chloro-6-(4-methoxyphenyl)thieno[3,2-d]pyrimidin-2-amine 

Relevant academic research and scientific papers

THIOETHER DERIVATIVES AS PROTEIN KINASE INHIBITORS

The present invention relates to thioether derivatives (1) as protein kinase inhibitors, which are useful for the treatment, relieve and/or prevention of diseases associated with abnormal and hyperproliferation of cells in a mammal, especially humans, and which are particularly useful for the treatment of all forms of cancer.

Synthesis of a novel series of thieno[3,2-d]pyrimidin-4-(3H)-ones

2-Aminothieno[3,2-d]pyrimidin-4-ones were synthesized in one step by condensation of 3-amino(benzo)thiophene car-boxylate with chloroformamidine hydrochloride. Georg Thieme Verlag Stuttgart.