1234804-84-2

Upstream product

• 1234804-82-0 (2R,5S)-1-benzyloxycarbonyl-2-methoxycarbonyl-5-(2-hydroxyethyl)pyrrolidine 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 936564-33-9 (1R,5S)-N-benzyloxycarbonyl-2-oxo-8-azabicyclo[3.2.1]octane 
• 1234804-83-1 (1R,5S)-8-benzyloxycarbonyl-2-(tert-butyl-dimethylsilyloxy)-8-azabicyclo[3.2.1]oct-2-ene 

Downstream Products

• 1234804-85-3 (2S,5R)-benzyloxycarbonyl-2-(2-(tert-butyldiphenylsilyloxy)ethyl)-5-formylpyrrolidine 
• 1234804-86-4 C₃₃H₄₁NO₄Si 
• 1234804-87-5 (2S,5R)-benzyloxycarbonyl-2-(2-(tert-butyldiphenylsilyloxy)ethyl)-5-(2-oxoethyl)pyrrolidine 
• 1234804-88-6 (2S,5S)-benzyloxycarbonyl-2-(2-(tert-butyldiphenylsilyloxy)ethyl)-5-(2-(2,6-dioxocyclohexyl)ethyl)pyrrolidine 

Relevant academic research and scientific papers

An enantioselective formal synthesis of (+)-Gephyrotoxin 287C

The tricyclic skeleton of the gephyrotoxin amphibian alkaloids was synthesized via an enantioselective serial sequence involving nine discrete steps that furnished Kishi's intermediate 5 in 22% overall yield. This efficient and expeditious synthetic approach exploits the inherent stereochemistry of a (1R)-2-tropinone derivative for the construction of the core cis-2,5-disubstituted pyrrolidine ring system and constitutes a formal synthesis of gephyrotoxin 287C. ARKAT USA, Inc.