1234845-77-2

Upstream product

• 128495-46-5 4-fluoro-3-methoxybenzaldehyde 
• 633335-94-1 1-fluoro-2-methoxy-4-vinylbenzene 

Downstream Products

• 1421502-78-4 C₂₉H₂₄FN₇O₂ 
• 1421502-75-1 C₂₉H₂₈FN₅O 
• 1421502-68-2 C₂₈H₂₄ClFN₆O₂ 
• 1421503-62-9 2-[6-(2-ethyl-5-fluoro-4-methoxy-phenyl)-1-(tetrahydro-pyran-2-yl)-1H-indazol-3-yl]-1-(2-trimethylsilanyl-ethoxymethyl)-4,5,7,8-tetrahydro-1H-imidazo[4,5-d]azepine-6-carboxylic acid tert-butyl ester 
• 1421503-55-0 2-[6-(2-ethyl-5-fluoro-4-methoxy-phenyl)-1-(tetrahydro-pyran-2-yl)-1H-indazol-3-yl]-1-(2-trimethylsilanyl-ethoxymethyl)-1,4,6,7-tetrahydro-imidazo[4,5-c]pyridine-5-carboxylic acid tert-butyl ester 
• 1421503-51-6 3-(trimethylstannyl)-6-(2-ethyl-5-fluoro-4-methoxyphenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole 
• 1421503-50-5 6-(2-ethyl-5-fluoro-4-methoxy-phenyl)-3-iodo-1-(tetrahydro-pyran-2-yl)-1H-indazole 
• 1421503-49-2 6-(2-ethyl-5-fluoro-4-methoxy-phenyl)-3-iodo-1H-indazole 
• 1421503-48-1 6-(2-ethyl-5-fluoro-4-methoxy-phenyl)-1H-indazole 
• 1421503-47-0 6-(2-ethyl-5-fluoro-4-methoxy-phenyl)-1-(tetrahydro-pyran-2-yl)-1H-indazole 
• 1421503-46-9 2-(2-ethyl-5-fluoro-4-methoxy-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 
• 1421503-45-8 1-bromo-2-ethyl-5-fluoro-4-methoxy-benzene 

Relevant academic research and scientific papers

FUSED IMIDAZO-PIPERIDINE JAK INHIBITOR COMPOUND

The invention provides a compound of formula 1 or a pharmaceutically-acceptable salt thereof, that is useful as a JAK inhibitor. The invention also provides crystalline forms of the compound, pharmaceutical compositions comprising the compound, methods of using the compound to treat diseases amenable to a JAK inhibitor, and processes and intermediates useful for preparing the compound.

GPR120 RECEPTOR AGONISTS AND USES THEREOF

GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.

GPR120 RECEPTOR AGONISTS AND USES THEREOF

GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.

GPR120 RECEPTOR AGONISTS AND USES THEREOF

GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.