1234908-93-0Relevant academic research and scientific papers
Enantioselective bromocyclization of allylic amides catalyzed by BINAP derivatives
Kawato, Yuji,Kubota, Akino,Ono, Hiromi,Egami, Hiromichi,Hamashima, Yoshitaka
supporting information, p. 1244 - 1247 (2015/03/14)
A highly enantioselective bromocyclization of allylic amides with N-bromosuccinimide (NBS) was developed with DTBM-BINAP as a catalyst, affording chiral oxazolines with a tetrasubstituted carbon center in high yield with up to 99% ee. By utilizing the bro
Nickel-catalyzed enantioselective hydrovinylation of silyl-protected allylic alcohols: An efficient access to homoallylic alcohols with a chiral quaternary center
Zhang, Qi,Zhu, Shou-Fei,Cai, Yan,Wang, Li-Xin,Zhou, Qi-Lin
experimental part, p. 1899 - 1906 (2011/02/25)
Asymmetric hydrovinylation of silyl-protected allylic alcohols catalyzed by nickel complexes of chiral spiro phosphoramidite ligands was developed. A series of homoallylic alcohols with a chiral quaternary center were produced in high yields (up to 97%) and high enantioselectivities (up to 95% ee). The reaction provides an efficient method for preparing bifunctional compounds with a chiral quaternary carbon center.
Synthesis of quaternary carbon centers via hydroformylation
Sun,Frimpong,Tan
supporting information; experimental part, p. 11841 - 11843 (2010/11/04)
The application of hydroformylation to the synthesis of quaternary carbon centers is reported. The synthesis of the highly substituted carbon is achieved by applying a catalytic amount of 1. Ligand 1 serves as a catalytic directing group by covalently and reversibly binding to both the substrate and catalyst. The intramolecular nature of the directing group strategy accelerates the hydroformylation reaction such that the reaction is performed at mild temperatures (35-55 °C) and with excellent regioselectivity (b:l > 94:6).
Syntheses of mono-, di-, and trifluorinated styrenic monomers
Walkowiak, Justyna,Del Campo, Teresa Martinez,Ameduri, Bruno,Gouverneur, Veronique
experimental part, p. 1883 - 1890 (2010/08/20)
Concise syntheses of gram quantities of three fluorinated -methylstyrenic monomers suitable for polymerisation studies are disclosed, all based on the use of reasonably priced commercially available starting materials and reagents. Georg Thieme Verlag Stuttgart New York.
