1235165-52-2

Upstream product

• 386213-23-6 ethyl 4-(2-bromoethoxy)-3-nitrobenzoate 
• 19013-10-6 ethyl 4-hydroxy-3-nitrobenzoate 
• 1235166-28-5 ethyl 4-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)ethoxy)-3-aminobenzoate 
• 1235166-54-7 4-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)ethoxy)-3-(3-methylthiophene-2-carboxamido)benzoic acid 
• 113-00-8 guanidine nitrate 
• 1235166-51-4 ethyl 4-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)ethoxy)-3-(3-methylthiophene-2-carboxamido)benzoate 
• 1235166-22-9 ethyl 4-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)ethoxy)-3-nitrobenzoate 

Relevant academic research and scientific papers

Synthesis and Na+/H+ exchanger inhibitory activity of benzoylguanidine derivatives

Twenty-two compounds of substituted benzoylguanidine derivatives were designed and synthesized as potent NHE1 inhibitors. Twelve compounds showed more potent NHE1 inhibitory activity than cariporide. The activities of compounds 7e, 7h and 7j (IC50/s