123530-13-2Relevant academic research and scientific papers
Synthesis of one-, two- and three-ring macrocyclic, bifunctional compounds for use in radiolabelling monoclonal antibodies
Ramli, Martalena,Dong, Ying,Lindoy, Leonard F.,Smith, Suzanne V.,Wilson, J. Gerald
, p. 77 - 83 (2007/10/03)
The synthesis of new linked bis- and tris-ring tetraazamacrocyclic (bifunctional) reagents for use in an alternative strategy for radiolabelling antibodies is described. For comparison with the above systems, a new single ring bifunctional system incorpor
A new convenient synthesis of bifunctional chelating agent 1-(4- aminobenzyl)-1,4,8,11-tetraazacyclotetradecane-N',N'',N'''-triacetic acid [1- (H2NBn-TETA)]
Maillet,Kwok,Noujaim,Snieckus
, p. 2659 - 2662 (2007/10/03)
A convenient and short synthesis (3 steps, 50% overall yield) of the bifunctional chelating agent 1-(4-aminobenzyl)-1,4,8,11 - tetraazacyclotetradecane - N'-, N''-, N'''- triacetic acid (4) via a boron- protection strategy is reported.
