1235325-58-2

Upstream product

• 1235325-55-9 N'-((2,6-dioxocyclohexylidene)methyl)-4-methylbenzenesulfonohydrazide 
• 499206-33-6 2,5,6,7-tetrahydro-4H-indazol-4-one 
• 98-59-9 p-toluenesulfonyl chloride 
• 504-02-9 1,3-cylohexanedione 
• 85302-07-4 2-(dimethylaminomethylene)cyclohexane-1,3-dione 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 1235325-60-6 5-bromo-1-tosyl-6,7-dihydro-1H-indazol-4(5H)-one 
• 1620564-50-2 (R)-3-bromo-N-(2,4-dimethoxybenzyl)-1-(4,5,6,7-tetrahydro-1H-indazol-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 1620564-51-3 (R)-3-bromo-N-(2,4-dimethoxybenzyl)-1-(1-methyl-4,5,6,7-tetrahydro-1H-indazol-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 1620564-52-4 (R)-3-bromo-N-(2,4-dimethoxybenzyl)-1-(2-methyl-4,5,6,7-tetrahydro-2H-indazol-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 1620564-53-5 (R)-4-(4-((2,4-dimethoxybenzyl)amino)-1-(1-methyl-4,5,6,7-tetrahydro-1H-indazol-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(4-(trifluoromethyl)pyridin-2-yl)benzamide 
• 1620564-54-6 (R)-4-(4-((2,4-dimethoxybenzyl)amino)-1-(2-methyl-4,5,6,7-tetrahydro-2H-indazol-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(4-(trifluoromethyl)pyridin-2-yl)benzamide 

Relevant academic research and scientific papers

BTK INHIBITORS

The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I or pharmaceutically acceptable salts thereof. Formula I or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising the

Aldosterone Synthase Inhibitor

The present invention provides aldosterone synthase inhibitors of the formula: intermediates, methods for their preparation, pharmaceutical preparations, and methods for their use.

HETEROTRICYCLIC COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS

The present invention relates to novel compounds of Formula (I), wherein wherein X1, X2, Y, Z1, Z2, Z3, M and (A)m are defined as in Formula (I); invention compounds are modulators of metab