1235332-88-3Relevant academic research and scientific papers
Dual catalysis by Cu(i): Facile single step click and intramolecular C-O bond formation leading to triazole tethered dihydrobenzodioxines/benzoxazines/ benzoxathiines/benzodioxepines
Nagarjuna Reddy,Kumara Swamy
, p. 7350 - 7360 (2013)
Dual copper catalysis, involving two different reactions, click (alkyne-azide) and carbon-oxygen bond formation (aryl iodide-secondary alcohol) in a single step, is reported. Synthesis of novel benzodioxines (benzodioxanes), benzoxazines, benzoxathiines and benzodioxepines, which feature benzo-condensed six or seven membered rings containing two hetero-atoms attached to a 1,2,3-triazole, is described. As an extension, such compounds were also synthesised by ring opening of epoxide and cyclisation using Cu(i). All the key products have been characterized by single crystal X-ray crystallography.
