123536-88-9

Upstream product

• 123536-87-8 3-methoxy-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-dioic acid dimethyl ester 
• 186581-53-3 diazomethane 
• 67-56-1 methanol 
• 102472-56-0 (+/-)-7a-methoxycarbonylmethyl-4c-(4-methoxy-phenyl)-7c-methyl-2-oxo-(3ar,7ac)-octahydro-benzofuran-7t-carboxylic acid methyl ester 
• 102472-56-0 (+/-)-7a-methoxycarbonylmethyl-4c-(4-methoxy-phenyl)-7c-methyl-2-oxo-(3ar,7at)-octahydro-benzofuran-7t-carboxylic acid methyl ester 
• 111089-11-3 rac-3-methoxy-16.17-seco-estratetraene-(1.3.5⁽¹⁰⁾.8)-dioic acid-(16.17)-dimethyl ester 
• 64-19-7 acetic acid 
• 110-86-1 pyridine 
• 111585-01-4 rac-14-hydroxy-3-methoxy-16.17-seco-8α.14ξ-estratriene-(1.3.5(10))-dioic acid-(16.17)-dimethyl ester 
• 10025-87-3 trichlorophosphate 
• 111585-01-4 (1-hydroxy-7-methoxy-2-methoxycarbonyl-2-methyl-1,2,3,4,4a,9,10,10a-octahydro-[1]phenanthryl)-acetic acid methyl ester 
• 979-70-4 rac-3-methoxy-16,17-seco-14β-estra-1,3,5(10)-triene-16,17-dioic acid dimethyl ester 
• 110663-44-0 rac-3-methoxy-6-oxo-16,17-seco-estra-1,3,5⁽¹⁰⁾-triene-16,17-dioic acid dimethyl ester 
• 110663-44-0 rac-3-methoxy-6-oxo-16,17-seco-14β-estra-1,3,5(10)-triene-16,17-dioic acid dimethyl ester 

Downstream Products

• 482-49-5 (+)-trans-doisynolic acid 
• 123456-16-6 (1S,2S,4aS,10aR)-7-Methoxy-2-methyl-1-[2-(toluene-4-sulfonyloxy)-ethyl]-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

15,16-seco-19-nor progestins

15,16-Seco-19-nor progestins are provided which display elevated progestational activity with a minimum of ancillary hormonal activity. Processes for the preparation of the novel progestins are provided as are methods of use. A preferred method of use is in the suppression of ovulation in the human female.

SYNTHESIS OF SOME NOVEL 16-AZAESTRONES AND 17-AZA-D-HOMOESTRONES. THE X-RAY CRYSTAL STRUCTURE OF 3-METHOXY-16-AZA-14β-1,3,5-(10)-ESTRATRIEN-15-ONE

The efficient syntheses of several new 16-azaestrones and 17-aza-D-homoestrones from estrone methyl ether are reported.These include 3-methoxy-17-aza-D-homo-1,3,5(10)-estratrien-17a-one (2), 3-methoxy-17-aza-D-homo-1,3,5(10)-estratrien-16-one (3) and the