123537-99-5

Upstream product

• 88559-61-9 ((2S,4S,6S)-4-Hydroxy-2-methoxy-6-methyl-tetrahydro-pyran-2-yl)-acetic acid tert-butyl ester 
• 116511-80-9 3-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propionic acid (R)-1-methyl-2-((S)-6-oxo-3,6-dihydro-2H-pyran-2-yl)-ethyl ester 
• 129987-26-4 (R)-4-Hydroxy-6-((R)-2-hydroxy-propyl)-tetrahydro-pyran-2-one 
• 116511-78-5 (5R,7R)-3,5,7-Trihydroxy-octanoic acid tert-butyl ester 
• 942292-99-1 (R)-6-[(R)-2-hydroxypropyl]-5,6-dihydro-2H-pyran-2-one 
• 116511-71-8 3,4-bis(O-tert-butyldimethylsilyl)-3,4-dihydroxyhydrocinnamic acid 
• 88559-60-8 ((2S,6S)-2-Methoxy-6-methyl-4-oxo-tetrahydro-pyran-2-yl)-acetic acid tert-butyl ester 
• 116511-79-6 3-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propionic acid (S)-2-((S)-2-{3-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propionyloxy}-propyl)-6-oxo-tetrahydro-pyran-4-yl ester 

Relevant academic research and scientific papers

A facile total synthesis of all stereoisomers of tarchonanthuslactone and euscapholide from chiral epichlorohydrin

A versatile and facile synthetic route to all the stereoisomers of tarchonanthuslactone and euscapholide was developed using epichlorohydrin as the source of all the chiral centers. Georg Thieme Verlag Stuttgart.

A Concise and Versatile Total Synthesis of All Stereoisomers of Tarchonanthuslactone

We describe the versatile and concise total synthesis of all stereoisomers of tarchonanthuslactone from (R)- or (S)-3-hydroxybutyrate via eight steps. The key steps of the synthesis include a highly diastereoselective chelation-controlled Mukaiyama aldol

DETERMINATION OF STEREOSTRUCTURE OF NATURALLY OCCURRING α,β-UNSATURATED δ-LACTONE DERIVATIVES THROUGH A STEREOSELECTIVE SYNTHESIS

The stereostructures of (-)-tarchonanthuslactone (2) and the δ-lactone of (Z)-5,7,9,11-tetrahydroxyhexacos-2-enoic acid (3) were established as 9 and 27 by the stereoselective syntheses of authentic 9 and 26 (triacetate of 3), respectively.