1235394-73-6

Basic information

• Product Name: cyclo[-Phe-Thr(ψ-^Me,Mepro)-Phe-Thr(ψ-^Me,Mepro)-]
• Synonyms: cyclo[-Phe-Thr(ψ-^Me,Mepro)-Phe-Thr(ψ-^Me,Mepro)-]
• CAS NO: 1235394-73-6
• Molecular Weight: 576.693
• Mol File: 1235394-73-6.mol

Chemical Properties

• CAS DataBase Reference: cyclo[-Phe-Thr(ψ-^Me,Mepro)-Phe-Thr(ψ-^Me,Mepro)-](CAS DataBase Reference)
• NIST Chemistry Reference: cyclo[-Phe-Thr(ψ-^Me,Mepro)-Phe-Thr(ψ-^Me,Mepro)-](1235394-73-6)
• EPA Substance Registry System: cyclo[-Phe-Thr(ψ-^Me,Mepro)-Phe-Thr(ψ-^Me,Mepro)-](1235394-73-6)

Safety Data

• Hazardous Substances Data: 1235394-73-6(Hazardous Substances Data)

Upstream product

• 1235394-64-5 NH2-Phe-Thr(ψ-^Me,Mepro)-Phe-Thr(ψ-^Me,Mepro)-OH 

Downstream Products

• 1235394-84-9 cyclo[Phe-Thr-Phe-Thr] 

Relevant articles and documents

Synthesis of All- L cyclic tetrapeptides using pseudoprolines as removable turn inducers

(Figure Presented) Cyclic tetrapeptides have generated great interest because of their broad-ranging biological properties. In order to synthesize these highly strained 12-membered cyclic compounds, a cyclization strategy using pseudoprolines as removable turn inducers has been developed. The pseudoproline derivatives induce a cisoid amide bond in the linear peptide backbone which facilitates cyclization. After cyclization, the turn inducers can be readily removed to afford cyclic tetrapeptides containing serine or threonine residues.