123541-74-2

Upstream product

• 118252-50-9 3-<2-(acetylamino)-4-(diacetylamino)-1,6-dihydro-6-oxo-5-pyrimidinyl>propionaldehyde diethyl acetal 
• 118252-49-6 3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propionaldehyde diethyl acetal 
• 118252-48-5 ethyl 2-cyano-5,5-diethoxypentanoate 
• 118252-51-0 2-acetamido-8-acetyl-5,6,7,8-tetrahydro-7-hydroxypyrido<2,3-d>pyrimidin-4(3H)-one 
• 62-53-3 aniline 

Downstream Products

• 123541-78-6 2,6-diamino-5-(3-anilinopropyl)-4(3H)-pyrimidinone 

Relevant academic research and scientific papers

Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propyl]amino]-b benzoyl]-L-glutamic acid

The synthesis and biological evaluation of N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl) propyl]amino]-benzoyl]-L-glutamic acid (1) (5-DACTHF, 543U76), an acyclic analogue of 5,6,7,8-tetrahydrofolic acid (TFHA), are described. The key intermediat