1235442-75-7Relevant academic research and scientific papers
Synthesis of biologically active phenoxy derivatives of substituted benzothiazole organophosphates
Jhajharia, Priyanka,Samota, Mahesh Kumar,Seth, Gita
experimental part, p. 84 - 88 (2011/04/22)
The reaction of S-(phenyl benzothiazolyl-2)phosphorodichloridothioate/ phosphorodichloridodithioatewith 2mol of phenol/4-chlorophenol/4-nitrophenol in the presence of stoichiometric amounts of triethylamine in dry THF/CH 2Cl2 has afforded a series of the corresponding organophosphate phenoxy derivatives (1a, 1b, 2a, 2b, and 3a, 3b). Plausible structures have been proposed on the basis of elemental analysis, IR, 1H NMR, 31P NMR, and mass spectral studies. The antibacterial activity of these organophosphate phenoxy derivatives has been evaluated against pathogenic bacteria Staphylococcus aureus (+ve) and Escherichia coli (-ve). The antifungal activity of these organophosphate phenoxy derivatives has been evaluated against pathogenic fungi Aspergillus niger and Fusarium oxysporium. The results indicate that organophosphate phenoxy derivatives are found more active than the parent compounds.
