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1235451-38-3

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1235451-38-3 Usage

General Description

N-Boc-5-Bromo-2-pyrimidinemethanamine is a chemical compound used as a building block in organic synthesis. It consists of a pyrimidine ring with a bromine atom and a N-Boc (tert-butoxycarbonyl) protective group attached to the nitrogen atom. The N-Boc group is commonly used to protect amines in organic reactions and can be easily removed under mild conditions. N-Boc-5-BroMo-2-pyriMidineMethanaMine can be used in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is important for its versatility as a chemical intermediate in the production of a wide range of compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 1235451-38-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,5,4,5 and 1 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1235451-38:
(9*1)+(8*2)+(7*3)+(6*5)+(5*4)+(4*5)+(3*1)+(2*3)+(1*8)=133
133 % 10 = 3
So 1235451-38-3 is a valid CAS Registry Number.

1235451-38-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-Butyl ((5-bromopyrimidin-2-yl)methyl)carbamate

1.2 Other means of identification

Product number -
Other names tert-butyl N-[(5-bromopyrimidin-2-yl)methyl]carbamate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1235451-38-3 SDS

1235451-38-3Downstream Products

1235451-38-3Relevant articles and documents

PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH ZINC BINDING MOIETY

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Paragraph 0423, (2016/10/07)

PROBLEM TO BE SOLVED: To provide phosphoinositide 3-kinase inhibitors with a zinc binding moiety. SOLUTION: There is provided a compound represented by formula (I) in the figure. (X is S, O or the like; Y is CH, N or the like; G1 is optionally substituted N or the like; R1 and R2 are each independently H or the like; C is a substituted heterocycle or the like; B is a linear alkyl or the like; Ra and Rb together with the nitrogen atom coupled to them are morpholino or the like; G2 is an indazole ring or the like; q, r and s are independently from 0 to 1, provided that at least one of them is 1; t is from 0 to 1; n is from 0 to 4; and p is from 0 to 2.) COPYRIGHT: (C)2016,JPOandINPIT

TREATMENT OF CANCERS HAVING K-RAS MUTATIONS

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Page/Page column 207, (2011/11/01)

The present invention provides a method of treating a cancer associated with a K- ras mutation in a subject in need thereof. The method comprises the steps of (1) identifying a subject with a cancer associated with a K-ras mutation; and (2) adminsiterign to the subject (i) an inhibitor of PI3 kinase and (ii) an HDAC inhibitor, wherein the PI3 kinase inhibitor and the HDAC inhibitor are administered in amounts which together are therapeutically effective.

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