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7-amino-3-(3-methoxyphenyl)-9H-carbazole-1-carboxamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1235462-50-6 Structure
  • Basic information

    1. Product Name: 7-amino-3-(3-methoxyphenyl)-9H-carbazole-1-carboxamide
    2. Synonyms: 7-amino-3-(3-methoxyphenyl)-9H-carbazole-1-carboxamide
    3. CAS NO:1235462-50-6
    4. Molecular Formula:
    5. Molecular Weight: 331.374
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1235462-50-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7-amino-3-(3-methoxyphenyl)-9H-carbazole-1-carboxamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7-amino-3-(3-methoxyphenyl)-9H-carbazole-1-carboxamide(1235462-50-6)
    11. EPA Substance Registry System: 7-amino-3-(3-methoxyphenyl)-9H-carbazole-1-carboxamide(1235462-50-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1235462-50-6(Hazardous Substances Data)

1235462-50-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1235462-50-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,5,4,6 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1235462-50:
(9*1)+(8*2)+(7*3)+(6*5)+(5*4)+(4*6)+(3*2)+(2*5)+(1*0)=136
136 % 10 = 6
So 1235462-50-6 is a valid CAS Registry Number.

1235462-50-6Relevant articles and documents

9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors

Zimmermann, Kurt,Sang, Xiaopeng,Mastalerz, Harold A.,Johnson, Walter L.,Zhang, Guifen,Liu, Qingjie,Batt, Douglas,Lombardo, Louis J.,Vyas, Dinesh,Trainor, George L.,Tokarski, John S.,Lorenzi, Matthew V.,You, Dan,Gottardis, Marco M.,Lippy, Jonathan,Khan, Javed,Sack, John S.,Purandare, Ashok V.

, p. 2809 - 2812 (2015/06/08)

The discovery, synthesis, and characterization of 9H-carbazole-1-carboxamides as potent and selective ATP-competitive inhibitors of Janus kinase 2 (JAK2) are discussed. Optimization for JAK family selectivity led to compounds 14 and 21, with greater than 45-fold selectivity for JAK2 over all other members of the JAK kinase family.

CARBAZOLE AND CARBOLINE KINASE INHIBITORS

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Page/Page column 116, (2010/08/04)

The present invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The Formula (I) compounds inhibit tyrosine kinase activity of Jak2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.

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