1235544-22-5Relevant academic research and scientific papers
Chemical protein synthesis by kinetically controlled ligation of peptide O-esters
Zheng, Ji-Shen,Cui, Hong-Kui,Fang, Ge-Min,Xi, Wei-An,Liu, Lei
, p. 511 - 515 (2010)
(Chemical Equation Presented) Designer peptides: A large reactivity difference was observed between two peptide O-esters that can undergo peptide ligation through an situ O-to-S acyl shift. This observation allowed the designed of "one-pot" N-to-C sequential peptide fragment condensation through kinetically controlled ligation with more readily accessible peptide O-esters.
