1235886-07-3Relevant academic research and scientific papers
Palladium-catalyzed direct oxidative Heck-Cassar-Sonogashira type alkynylation of indoles with alkynes under oxygen
Yang, Luo,Zhao, Liang,Li, Chao-Jun
supporting information; experimental part, p. 4184 - 4186 (2010/08/19)
A novel PdII catalyzed direct oxidative Heck-Cassar-Sonogashira type alkynylation of indoles with terminal alkynes under an atmosphere of O 2 is developed. Unlike previous methods, the reaction does not require the pregeneration of indolyl halide or alkynyl halide. Furthermore, only a catalytic amount of base is required and oxygen was used as the ultimate green terminal oxidant.
