123595-50-6Relevant articles and documents
Heteroatom-Assisted Substitution of Acyclic Secondary Tosylates with Lithium Dialkylcuprates: An Expedient Route to Stereochemically Defined Deoxypropionate and Related Biosynthetic Subunits
Hanessian, S.,Thavonekham, B.,DeHoff, B.
, p. 5831 - 5833 (2007/10/02)
Secondary tosylates of a number of acyclic molecules can be easily displaced with diorganocuprates with complete inversion of configuration.The displacement reaction is greatly facilitated when a hetero atom (S or O) is proximal to the nucleofugal group a