123595-49-3Relevant articles and documents
Screening of a virtual mirror-image library of natural products
Noguchi, Taro,Oishi, Shinya,Honda, Kaori,Kondoh, Yasumitsu,Saito, Tamio,Ohno, Hiroaki,Osada, Hiroyuki,Fujii, Nobutaka
, p. 7653 - 7656 (2016/07/06)
We established a facile access to an unexplored mirror-image library of chiral natural product derivatives using d-protein technology. In this process, two chemical syntheses of mirror-image substances including a target protein and hit compound(s) allow the lead discovery from a virtual mirror-image library without the synthesis of numerous mirror-image compounds.
Synthesis of the C15-C27 portion of venturicidins: A formal total synthesis of venturicidin X
Tsunashima, Keiji,Ide, Mitsuaki,Kadoi, Hiroshi,Hirayama, Aya,Nakata, Masaya
, p. 3607 - 3611 (2007/10/03)
The C15-C27 portion of venturicidin X was prepared using substitution reactions of alkyl trifluoromethanesulfonates with a vinylmetal compound followed by homogeneous hydrogenation. Together with our previous synthesis of the C1-C14 portion of venturicidin X, a formal total synthesis of venturicidin X was completed.