1236-72-2 Usage
Uses
Used in Research Studies:
1,3,5(10)-ESTRATRIEN-2,3,16ALPHA,17BETA-TETROL 2-METHYL ETHER is used as a research tool for investigating the biological effects of estrogen on various physiological processes. Its structural similarity to estradiol allows scientists to study the interactions of estrogen with its receptors and the subsequent effects on cellular and molecular pathways.
Used in Hormone Replacement Therapy:
1,3,5(10)-ESTRATRIEN-2,3,16ALPHA,17BETA-TETROL 2-METHYL ETHER is being studied for its potential use in hormone replacement therapy. Its ability to bind to estrogen receptors suggests that it may help alleviate symptoms associated with hormonal imbalances, such as those experienced during menopause.
Used in Treatment of Hormonal Imbalance Conditions:
1,3,5(10)-ESTRATRIEN-2,3,16ALPHA,17BETA-TETROL 2-METHYL ETHER is being explored as a potential treatment for conditions related to hormonal imbalances. Its interaction with estrogen receptors may help regulate hormone levels and improve symptoms associated with such imbalances.
Check Digit Verification of cas no
The CAS Registry Mumber 1236-72-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,3 and 6 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1236-72:
(6*1)+(5*2)+(4*3)+(3*6)+(2*7)+(1*2)=62
62 % 10 = 2
So 1236-72-2 is a valid CAS Registry Number.
InChI:InChI=1/C19H26O4/c1-19-6-5-11-12(14(19)9-16(21)18(19)22)4-3-10-7-15(20)17(23-2)8-13(10)11/h7-8,11-12,14,16,18,20-22H,3-6,9H2,1-2H3/t11-,12+,14-,16+,18-,19-/m0/s1
1236-72-2Relevant academic research and scientific papers
Synthesis of 2-Methoxy- and 4-Methoxy-Estrogens with Halogen-Methoxy Exchange Reaction
Numazawa, Mitsuteri,Ogura, Yuko,Kimura, Katsuhiko,Nagaoka, Masao
, p. 3701 - 3715 (2007/10/02)
Synthesis of 2-methoxy- and 4-methoxy-estrone (6) and (9), 2-methoxy- and 4-methoxy-estradiol (15) and (18), and 2-methoxy- and 4-methoxy-estratriol (24) and (27) are described.Catalytic hydrogenation over Pd/C of 2,4-dibromo or 2,4-diiodo estrogens gave regioselectively the corresponding 4-halogeno derivatives in excellent yields.Reaction of 2-iodo or 4-iodo estradiol and 2-iodo or 4-iodo estriol with NaOCH3 in MeOH and dimethylformamide (DMF) in the presence of CuCl2 gave in an excellent yield and in a good yield, while (6) and (9) were also similarly obtained by the reaction with pyridine instead of DMF.
Efficient Synthesis of 2-Methoxy- and 4-Methoxy-estrogens
Numazawa, Mitsuteru,Ogura, Yuko
, p. 533 - 534 (2007/10/02)
2-Methoxy- and 4-methoxy-estrogens are easily prepared from the corresponding 2-iodo or 4-bromo derivatives in high yields by a halogen-methoxy group exchange reaction using sodium methoxide-copper(II) chloride.
