1236057-20-7

Basic information

• Product Name: 4-[(1H-indol-3-yl)methyl]-N-ethyl-N-methylbenzenamine
• Synonyms: 4-[(1H-indol-3-yl)methyl]-N-ethyl-N-methylbenzenamine
• CAS NO: 1236057-20-7
• Molecular Weight: 264.37
• Mol File: 1236057-20-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-[(1H-indol-3-yl)methyl]-N-ethyl-N-methylbenzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(1H-indol-3-yl)methyl]-N-ethyl-N-methylbenzenamine(1236057-20-7)
• EPA Substance Registry System: 4-[(1H-indol-3-yl)methyl]-N-ethyl-N-methylbenzenamine(1236057-20-7)

Safety Data

• Hazardous Substances Data: 1236057-20-7(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 50-00-0 formaldehyd 
• 613-97-8 N-methyl-N-ethylaniline 
• 75-05-8 acetonitrile 

Relevant articles and documents

Visible-Light-Promoted Alkylation of Indoles with Tertiary Amines by the Oxidation of a sp3 C-H Bond

A visible-light driven reaction for the synthesis of 3-arylmethyl indole derivatives using tertiary amines and indoles was first reported. Corresponding products were obtained with yields of up to 70%, and various functional groups on the indoles were well tolerated when Rose Bengal was used as a photosensitizer and air was used as a green oxidant under mild reaction conditions. (Figure presented.).

Ruthenium-catalyzed alkylation of indoles with tertiary amines by oxidation of a sp3 CH bond and lewis acid catalysis

Ruthenium porphyrins (particularly [Ru(2,6-Cl2tpp)CO]; tpp = tetraphenylporphinato) and RuCl3 can act as oxidation and/or Lewis acid catalysts for direct C-3 alkylation of indoles, giving the desired products in high yields (up to 82