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5-benzoyl-2-benzyl-8-methylthio-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1236142-53-2

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1236142-53-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1236142-53-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,6,1,4 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1236142-53:
(9*1)+(8*2)+(7*3)+(6*6)+(5*1)+(4*4)+(3*2)+(2*5)+(1*3)=122
122 % 10 = 2
So 1236142-53-2 is a valid CAS Registry Number.

1236142-53-2Downstream Products

1236142-53-2Relevant academic research and scientific papers

Synthesis and biological activity of N-aroyl-tetrahydro-γ-carbolines

Bridoux, Alexandre,Millet, Régis,Pommery, Jean,Pommery, Nicole,Henichart, Jean-Pierre

experimental part, p. 3910 - 3924 (2010/08/05)

Research on dual inhibitors of both 5-LOX and COXs gained interest due to the overexpressions of these enzymes during the malignant state of the evolution of prostate cancer. In order to take part in this research, new N-aroyl-tetrahydro-γ-carbolines issued from the modification of Indomethacin have been synthesised. As for the NSAIDs, the compounds have been tested for their activity against COX1, COX2 plus against 5-LOX and against the proliferation of malignant prostate cancer. Interesting cytotoxic activities and selectivities of some tetrahydro-γ-carboline derivatives have been obtained.

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