1236189-75-5Relevant academic research and scientific papers
Chemical and biocatalytical methods of determination of stereomeric composition of 1,4-di[(diethoxylphosphoryl)hydroxymethyl]benzene
Malinowska, Barbara,Mlynarz, Piotr,Lejczak, Barbara
, p. 299 - 313 (2013/09/24)
Reaction of terephtalaldehyde with diethyl phosphite catalyzed by potassium fluoride and alumina has been intensively studied in the literature because of its stereoselective course which, despite of using non-chiral substrates, results in a predominant formation of one diastereoisomer. However, the absolute configuration of the formed 1,4-di[(diethoxyphosphoryl)hydroxymethyl]benzene remains to be undefined so far, because of its high symmetry and thus the failure of the methods commonly used in stereochemistry. Application of stereoselective biocatalysis appeared to be a successful way to help to determine stereomeric composition of this compound, which was resolved as RR/SS mixture. ARKAT-USA, Inc.
Long range phosphorus-phosphorus coupling constants in bis(phosphorylhydroxymethyl)benzene derivatives
Doskocz, Marek,Malinowska, Barbara,M?ynarz, Piotr,Lejczak, Barbara,Kafarski, Pawe?
supporting information; body text, p. 3406 - 3411 (2010/08/22)
Long range spin-spin couplings found between two phosphorus atoms are quite rare phenomena. A new example of such a coupling through seven bonds is described for 1-[(diethoxyphosphoryl)butyryloxymethyl]-4-[(diethoxyphosphoryl)hydroxymethyl]benzene and 1,4-bis[phosphorylhydroxymethyl]benzene and through six bonds for tetraethyl phenylene-1,3-(bishydroxymethylphosphonate). Coupling constants in this system are also well predicted by theoretical studies.
