123629-41-4

Upstream product

• 141-97-9 ethyl acetoacetate 
• 123-08-0 4-hydroxy-benzaldehyde 
• 57-13-6 urea 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 5173-27-3 1,2-bis(4-hydroxyphenyl)-ethane-1,2-diol 
• 1185842-96-9 1,1'-[(4-hydroxyphenyl)methylene]diurea 

Downstream Products

• 874672-92-1 6-Methyl-4-(4-oxiranylmethoxy-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester 
• 1403815-79-1 C₁₆H₁₈N₂O₅ 
• 1272318-40-7 C₁₄H₁₄N₂O₄ 
• 1402085-56-6 (E)-4-(4-hydroxy-phenyl)-6-(4-hydroxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid 

Relevant academic research and scientific papers

Cu(II) immobilized on mesoporous organosilica as an efficient and reusable nanocatalyst for one-pot Biginelli reaction under solvent-free conditions

Cu(II) immobilized on mesoporous organosilica nanoparticles (Cu2+@MSNs-(CO2 ?)2) has been synthesized, as a inorganic–organic nanohybrid catalyst, through a post-grafting approach. Its characterization is carrie

Zirconia Sulfuric Acid: An Efficient Heterogeneous Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidinones Under Solvent-Free Conditions

Abstract: In this article, zirconia sulfuric acid (ZrSA) has been synthesized from the reaction of ZrO2 with chlorosulfonic acid. It was characterized by (FT-IR, XRD, TGA, SEM, EDS, BET, BJH, ICP and pH analysis). This catalyst was employed for

Phenylboronic acid as a mild and efficient catalyst for Biginelli reaction

The synthesis of 3,4-dihydropyrimidinone derivatives was achieved in good to excellent yields using phenylboronic acid as catalyst to promote the Biginelli three-component condensation of a diversity of aromatic aldehydes, ethyl acetoacetate and urea or t

Zirconium(IV) chloride catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones

Zirconium tetrachloride catalyzes efficiently the three component condensation reaction of an aromatic aldehyde, a β-ketoester and urea in refluxing ethanol to afford the corresponding dihydropyrimidinone in high yield.

Magnetic Silica-Coated Picolylamine Copper Complex [Fe3O4@SiO2@GP/Picolylamine-Cu(II)]-Catalyzed Biginelli Annulation Reaction

An efficient and heterogeneous novel magnetic silica-coated picolylaminecopper complex [Fe3O4@SiO2@GP/Picolylamine-Cu(II)] was synthesized, characterized, and employed as a magnetically recoverable nanocatalyst in Biginelli condensation for the preparatio

Fabrication of porous ultrathin carbon nitride nanosheet catalysts with enhanced photocatalytic activity for N- And O-heterocyclic compound synthesis

A simple and efficient photocatalytic method for the synthesis of dihydropyrimidinones (DHPMs) and their derivatives via porous ultrathin carbon nitride nanosheets (p-CNNs) without solvents was demonstrated. The yields of 3,4-dihydropyrimidin-2(1H)-ones/t

Poly(N-vinyl-2-pyrrolidone)-supported ferric chloride: An effective reusable heterogeneous catalyst for one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones via three-component Biginelli reaction

An environmentally benign three-component Biginelli protocol for the one-pot synthesis of substituted 3,4-dihydropyrimidin-2(1H)-ones/thiones using an accessible, nontoxic, easy to handle, and recoverable macromolecular Lewis acidic catalyst is developed.

Sulfonic Acid and Ionic Liquid Functionalized Covalent Organic Framework for Efficient Catalysis of the Biginelli Reaction

A quinoline-linked and ionic liquid-decorated covalent organic framework was prepared by incorporation of a multicomponent Povarov reaction and postsynthetic modification. The imidazolium and sulfonic acid-decorated COF-IM-SO3H can be a highly efficient B

RETRACTED ARTICLE: Boric acid in magnetized water: Clean and powerful media for synthesis of 3,4-dihydropyrimidin-2(1: H)-ones

Water was magnetized via an external magnetic field and employed, for the first time, as a solvent in green preparation of 3,4-dihydropyrimidin-2(1H)-ones by the one-pot three-component condensation reaction using boric acid as a catalyst. Shorter reactio

Efficient biocatalytic strategy for one-pot Biginelli reaction via enhanced specific effects of microwave in a circulating reactor

A one-pot efficient biocatalytic strategy for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones was developed in a circulating microwave reactor selecting α-chymotrypsin as the promiscuous biocatalyst. In the circulating reaction system, the combination o