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1236352-56-9

[(18)F]-Raltegravir is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1236352-56-9 Structure

  • Basic information

    1. Product Name: [(18)F]-Raltegravir
    2. Synonyms:
    3. CAS NO:1236352-56-9
    4. Molecular Formula:
    5. Molecular Weight: 443.424
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1236352-56-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: [(18)F]-Raltegravir(CAS DataBase Reference)
    10. NIST Chemistry Reference: [(18)F]-Raltegravir(1236352-56-9)
    11. EPA Substance Registry System: [(18)F]-Raltegravir(1236352-56-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1236352-56-9(Hazardous Substances Data)

1236352-56-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1236352-56-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,6,3,5 and 2 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1236352-56:
(9*1)+(8*2)+(7*3)+(6*6)+(5*3)+(4*5)+(3*2)+(2*5)+(1*6)=139
139 % 10 = 9
So 1236352-56-9 is a valid CAS Registry Number.

1236352-56-9Downstream Products

1236352-56-9Relevant articles and documents

Radiosynthesis of the HIV integrase inhibitor [18F]MK-0518 (Isentress)

Li, Wenping,Thompson, Wayne,Fisher, Thorsten,Wai, John S.,Hazuda, Daria,Burns, H. Donald,Hamilla, Terence G.

, p. 517 - 520 (2010)

The human immunodeficiency virus integrase inhibitor, [18F]MK- 0518, was prepared via a three-step, one-pot radiosynthesis. [ 18F]4-Fluorobenzylamine was produced from the fluorination of 4-cyano-N,N,N-trimethylammonium triflate with [18F]fluoride and reduction with borane methylsulfide complex in 50-68% radiochemical yield. The final step, the coupling of [18F]4-fluorobenzylamine with an ester coupling partner, achieved an overall uncorrected radiochemical yield after HPLC purification of ～2%, based on the starting [18F]fluoride. In a typical run, the total synthesis time was about 90 min and gave 0.37-1.74 GBq (10-47 mCi) of [18F]MK-0518. The radiochemical purity of [ 18F]MK-0518 was >98% and the specific activity was 243-1275 Ci/mmol (EOS, n = 4). A convenient three-step, one-pot radiosynthesis of [ 18F]MK-0518 via [18F]4-fluorobenzylamine has been developed, giving sufficient quantities of [18F]MK-0518 for animal positron emission tomography studies. Copyright

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