1236375-83-9Relevant academic research and scientific papers
Discovery of a potent and short-acting oral calcilytic with a pulsatile secretion of parathyroid hormone
Shinagawa, Yuko,Inoue, Teruhiko,Katsushima, Takeo,Kiguchi, Toshihiro,Ikenogami, Taku,Ogawa, Naoki,Fukuda, Kenji,Hirata, Kazuyuki,Harada, Kazuhito,Takagi, Masaki,Nakagawa, Takashi,Kimura, Shuichi,Matsuo, Yushi,Maekawa, Mariko,Hayashi, Mikio,Soejima, Yuki,Takahashi, Mitsuru,Shindo, Masanori,Hashimoto, Hiromasa
scheme or table, p. 238 - 242 (2011/04/26)
Short-acting oral calcilytics, calcium-sensing receptor (CaSR) antagonists, have been considered as alternatives for parathyroid hormone (PTH), an injectable bone anabolic drug used in the treatment of osteoporosis. Previously, we identified aminopropandi
New aminopropandiol derivatives as orally available and short-acting calcium-sensing receptor antagonists
Shinagawa, Yuko,Inoue, Teruhiko,Hirata, Kazuyuki,Katsushima, Takeo,Nakagawa, Takashi,Matsuo, Yushi,Shindo, Masanori,Hashimoto, Hiromasa
scheme or table, p. 3809 - 3813 (2010/08/20)
Synthesis and structure-activity relationship studies on a new aminopropandiol class of derivatives as calcium-sensing receptor antagonists are described. Modification of the phenolic moiety of a calcilytic compound NPS 2143 led to the identification of a
