182964-49-4

Usage

Uses

Used in Pharmaceutical Industry:
Benzonitrile, 2-(1-hydroxyethyl)(9CI) is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its presence in the molecular structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, Benzonitrile, 2-(1-hydroxyethyl)(9CI) serves as a crucial component in the production of pesticides and other agrochemicals. Its unique properties contribute to the effectiveness and performance of these products in agricultural settings.
Used in Chemical Reactions:
Benzonitrile, 2-(1-hydroxyethyl)(9CI) is utilized as a versatile intermediate in a wide range of chemical reactions. Its ability to participate in various chemical processes makes it an essential component in the synthesis of a diverse array of products.
It is important to handle Benzonitrile, 2-(1-hydroxyethyl)(9CI) with care and adhere to proper safety protocols to minimize potential hazards associated with its use.

Upstream product

• 551-93-9 2-aminoacetophenone 
• 7468-67-9 o-formylbenzonitrile 

Downstream Products

• 1236375-83-9 C₁₂H₁₃NO₂ 
• 182963-65-1 2-(1-hydroxyethyl)benzylamine 

Relevant academic research and scientific papers

Candida tenuis xylose reductase catalysed reduction of acetophenones: The effect of ring-substituents on catalytic efficiency

The catalytic efficiencies of Candida tenuis xylose reductase catalysed reductions of mono-substituted acetophenones are in reasonable correlation with the σ-Hammett coefficients of the substituted phenyl groups. Variations of the substrate transformation rates are hence mainly caused by mesomeric and inductive effects of the substituents, while differences in substrate binding have a secondary relevance. Some substrate 1H NMR chemical shifts and carbonyl IR absorption bands are in reasonable accordance with the catalytic activities and allow the estimation of the transformation rates with good accuracy. The resulting substituted (S)-1-phenyl ethanols are generated in very high enantiomeric excess.

Imidazoquinazoline derivatives

The present invention relates to imidazoquinazoline derivatives represented by formula (I): STR1 wherein R1 represents hydrogen, substituted or unsubstituted lower alkyl, cycloalkyl, lower alkenyl, substituted or unsubstituted aralkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroarylalkyl, or substituted or unsubstituted heteroaryl, R2 and R3 represent independently hydrogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aralkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroarylalkyl, or substituted or unsubstituted heteroaryl, or R2 and R3 are combined to represent a heterocyclic group containing a nitrogen atom, R4 represents hydrogen or substituted or unsubstituted lower alkyl, X represents O or S, Y represents a single bond or O, n represents 0, 1, 2, or 3, and pharmaceutically acceptable salts thereof.