1236385-06-0Relevant academic research and scientific papers
Unexpected and divergent reactions of N -formyl-1,2-dihydroquinolines with sodium azide: Highly chemoselective formation of 2-substituted quinolines and isoxazolo[4,3- c ]quinolines
Su, Weike,Yu, Jingbo,Li, Zhenhua,Zheng, Bei
supporting information; experimental part, p. 1281 - 1284 (2010/07/03)
Efficient and divergent synthesis of 2-substituted quinolines and isoxazolo[4,3-c]quinolines was achieved from N-formyl-1,2-dihydroquinolines with the aid of sodium azide. The synthesis is substituent-dependent. Thus N-formyl-1,2-dihydroquinolines with a hydrogen atom at the 3-position afforded 2-substituted quinolines in good to excellent yields, while with a 3-formyl group, N-formyl-1,2-dihydroquinolines unexpectedly gave isoxazolo[4,3-c] quinolines in high yields. Georg Thieme Verlag Stuttgart.
