1236385-08-2Relevant academic research and scientific papers
Chromene- And quinoline-3-carbaldehydes: Useful intermediates in the synthesis of heterocyclic scaffolds
Rocha, Djenisa H.A.,Batista, Vasco F.,Balsa, Emanuel J.F.,Pinto, Diana C.G.A.,Silva, Artur M.S.
, (2020/10/02)
Chromenes and quinolines are recognized as important scaffolds in medicinal chemistry. Herein, the efficient use of chromene- and quinoline-3-carbaldehydes to synthesize other valuable heterocycles is described. These carbaldehydes are obtained in excelle
Unexpected and divergent reactions of N -formyl-1,2-dihydroquinolines with sodium azide: Highly chemoselective formation of 2-substituted quinolines and isoxazolo[4,3- c ]quinolines
Su, Weike,Yu, Jingbo,Li, Zhenhua,Zheng, Bei
supporting information; experimental part, p. 1281 - 1284 (2010/07/03)
Efficient and divergent synthesis of 2-substituted quinolines and isoxazolo[4,3-c]quinolines was achieved from N-formyl-1,2-dihydroquinolines with the aid of sodium azide. The synthesis is substituent-dependent. Thus N-formyl-1,2-dihydroquinolines with a hydrogen atom at the 3-position afforded 2-substituted quinolines in good to excellent yields, while with a 3-formyl group, N-formyl-1,2-dihydroquinolines unexpectedly gave isoxazolo[4,3-c] quinolines in high yields. Georg Thieme Verlag Stuttgart.
