123653-63-4Relevant academic research and scientific papers
Indan derivatives used for treating thromboses or asthma
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, (2008/06/13)
Method for the treatment or prophylaxis of thromboses or asthma in warm-blooded animal which comprises administering an effective amount of a compound having the formula: STR1 wherein R1 is phenyl group or phenyl group substituted by a member s
Indan derivatives and pharmaceutical preparation thereof
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, (2008/06/13)
Indan derivatives of the formula: STR1 wherein R1 is substituted or unsubstituted phenyl, naphthyl or sulfur-containing heterocyclic group, and R2 is hydroxy-methyl or a group of the formula: STR2 wherein R3 is hydrogen atom or lower alkyl and R4 is cycloalkyl, lower alkoxycarbonyl-phenyl, carboxy-phenyl, nitrogen-containing heterocyclic group, lower alkyl, or lower alkyl having a substituent selected from lower alkoxycarbonyl, carboxy, lower alkoxycarbonyl-phenyl, carboxy-phenyl, lower alkoxycarbonyl-cycloalkyl and carboxy-cycloalkyl, or a pharmaceutically acceptable salt thereof, which are useful as a platelet aggregation-inhibiting agent and as an agent for the treatment, amelioration and/or prophylaxis of a variety of thrombosis or embolism, coronary and cerebral vascular smooth muscle vellication, asthma, and the like, processes for the preparation thereof, and pharmaceutical composition containing said compound as an active ingredient.
