123657-20-5

Basic information

• Product Name: (2-Amino-thiazol-4-yl)-[(Z)-cyclohexyloxyimino]-acetyl chloride; hydrochloride
• Synonyms: (2-Amino-thiazol-4-yl)-[(Z)-cyclohexyloxyimino]-acetyl chloride; hydrochloride
• CAS NO: 123657-20-5
• Molecular Weight: 324.231
• Mol File: 123657-20-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-Amino-thiazol-4-yl)-[(Z)-cyclohexyloxyimino]-acetyl chloride; hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Amino-thiazol-4-yl)-[(Z)-cyclohexyloxyimino]-acetyl chloride; hydrochloride(123657-20-5)
• EPA Substance Registry System: (2-Amino-thiazol-4-yl)-[(Z)-cyclohexyloxyimino]-acetyl chloride; hydrochloride(123657-20-5)

Safety Data

• Hazardous Substances Data: 123657-20-5(Hazardous Substances Data)

Upstream product

• 68401-44-5 2-(2-amino-4-thiazolyl)-(Z)-2-cyclohexyloxyinoacetic acid 

Downstream Products

• 110717-56-1 6-<2-(2-amino-4-thiazolyl)-(Z)-2-cyclohexyloxyiminoacetamido>penicillanic acid 
• 123657-21-6 7-<2-(2-amino-4-thiazolyl)-(Z)-2-cyclohexyliminoacetamido>deacetoxycephalosporanic acid 

Relevant articles and documents

NEW SYNTHESIS OF OXIME-TYPE BETA-LACTAM ANTIBIOTICS

Reacton of anhydrous acids II with phosphorus pentachloride afforded hydrochlorides of chlorides III which were used in acylations of N,O-bis(trimethylsilyl) derivatives of 6-aminopenicillanic acid and 7-aminodeacetoxycephalosporanic acid.Change of the (Z)-configuration of the alkoxyimino group during the synthesis was observed only in the methoxyimino series.The prepared penicillins IV are effective against gram-positive as well as gram-negative bacteria.