1236769-46-2Relevant academic research and scientific papers
Iron-catalyzed C-O bond activation for the synthesis of propargyl-1,2,3-triazoles and 1,1-bis-triazoles
Yan, Wuming,Wang, Qiaoyi,Chen, Yunfeng,Petersen, Jeffrey L.,Shi, Xiaodong
supporting information; experimental part, p. 3308 - 3311 (2010/10/19)
(Equation Presented). The FeCl3-catalyzed triazole propargylation was developed. This transformation was suitable for a large scope of substituted propargyl alcohols, giving the corresponding propargyl triazoles in excellent yields (up to 96%). Further derivatization produced the 1,1-bis-triazoles in excellent yields and regioselectivity, which could be applied as potential transition metal ligands or new reagents.
