73922-80-2

Basic information

• Product Name: (R)-(+)-1-phenylhept-2-yn-1-ol
• Synonyms: (R)-(+)-1-phenylhept-2-yn-1-ol
• CAS NO: 73922-80-2
• Molecular Weight: 188.269
• Mol File: 73922-80-2.mol
• Article Data: 77

Chemical Properties

• CAS DataBase Reference: (R)-(+)-1-phenylhept-2-yn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-1-phenylhept-2-yn-1-ol(73922-80-2)
• EPA Substance Registry System: (R)-(+)-1-phenylhept-2-yn-1-ol(73922-80-2)

Safety Data

• Hazardous Substances Data: 73922-80-2(Hazardous Substances Data)

Upstream product

• 32359-01-6 hexenylmagnesium bromide 
• 100-52-7 benzaldehyde 
• 18998-78-2 1-phenyl-hept-2-yn-1-one 
• 1846-67-9 hept-2-ynal 
• 693-02-7 hex-1-yne 
• 591-50-4 iodobenzene 
• 1252684-61-9 hex-1-yn-1-yltrimethoxysilane 
• 542-69-8 1-iodo-butane 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 74-96-4 ethyl bromide 
• 766-97-2 4-n-methylphenylacetylene 
• 1119-67-1 1-iodo-1-hexyne 
• 3844-94-8 1-(trimethylsilyl)-1-hexyne 
• 218793-76-1 triethoxy(hex-1-yn-1-yl)silane 

Downstream Products

• 127624-06-0 4-(<1-(2-phenylethenylidene)pentyl>sulfinyl)morpholine 
• 53403-90-0 1-phenyl-3-hepten-1-one 
• 64235-53-6 (E)-1-phenyl-2-hepten-1-one 
• 19184-21-5 (E)-1-phenylhept-1-en-3-one 
• 19184-21-5 (1Z)-1-phenylhept-1-en-3-one 
• 113474-95-6 1-phenyl-(2E,4E)-hepta-2,4-dien-1-one 
• 648433-39-0 1-(dec-1-en-5-yn-4-yl)benzene 

Relevant articles and documents

Rhodium-Catalyzed C?H Activation/Annulation Cascade of Aryl Oximes and Propargyl Alcohols to Isoquinoline N-Oxides

A β-hydroxy elimination instead of common oxidization to carbonyl group in secondary propargyl alcohols was successfully developed to form 2-benzyl substituted isoquinoline N-oxides by a Rhodium-catalyzed C?H activation and annulation cascade, in which moderate to excellent yields (up to 92%) could be obtained under mild reaction conditions, along with good regioselectivity, broad generality and applicability. (Figure presented.).

Au(I)-catalyzed cycloaddition pathways of non-terminal propargyl substrates

Novel chiral menthol-based pyridyl nitrone ligands were synthesized and Au(I) coordination of the ligands gave chiral Au(I)–nitrone complexes. 1H NMR studies of the gold(I) coordination experiments with nitrone ligands afforded a convenient method for monitoring complex formation. The catalytic effect of Au(I)–nitrone complexes, shown to tune catalytic systems to produce uncommon products, was evaluated in [2 + 2 + 2] cyclotrimerization and [2 + 4] cyclodimerization reactions of non-terminal propargyl acetals. Alternative gold(I)-catalyzed [2 + 2], [2 + 4] and [3 + 4] cycloaddition reaction pathways of non-terminal propargyl acetals with imine substrates gave a diverse range of N-heterocyclic products. The present screening study demonstrates the potential and the versatility of non-terminal propargyl acetals in gold(I)-catalyzed cycloaddition reactions.

Dramatic enantioselectivity reversal in the propargylation of aldehyde with alkynyllithium catalyzed by dilithium binaphtholate derivatives

A slight structural modification of a chiral catalyst caused a dramatic reversal in the enantioselectivity of an aldehyde propargylation using alkynyllithium.