1236769-62-2Relevant academic research and scientific papers
The first multicomponent synthesis of propargyl-1,2,3-triazoles
Das, Biswanath,Bhunia, Nisith,Lingaiah, Maram,Reddy, Parigi Raghavendar
experimental part, p. 2625 - 2628 (2011/10/01)
The three-component reaction of benzotriazoles, aldehydes, and alkynes has been carried out for the first time using zinc bromide as a catalyst. The corresponding propargylbenzotriazoles are formed in high yields (79-97%) within 6-10 hours. Georg Thieme V
Iron-catalyzed C-O bond activation for the synthesis of propargyl-1,2,3-triazoles and 1,1-bis-triazoles
Yan, Wuming,Wang, Qiaoyi,Chen, Yunfeng,Petersen, Jeffrey L.,Shi, Xiaodong
supporting information; experimental part, p. 3308 - 3311 (2010/10/19)
(Equation Presented). The FeCl3-catalyzed triazole propargylation was developed. This transformation was suitable for a large scope of substituted propargyl alcohols, giving the corresponding propargyl triazoles in excellent yields (up to 96%). Further derivatization produced the 1,1-bis-triazoles in excellent yields and regioselectivity, which could be applied as potential transition metal ligands or new reagents.
