123730-03-0

Basic information

• Product Name: 7-methyl-2-(2'-nitrophenyl)imidazo<1,2-a>pyridine
• Synonyms: 7-methyl-2-(2'-nitrophenyl)imidazo<1,2-a>pyridine
• CAS NO: 123730-03-0
• Molecular Weight: 253.26
• Mol File: 123730-03-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 7-methyl-2-(2'-nitrophenyl)imidazo<1,2-a>pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methyl-2-(2'-nitrophenyl)imidazo<1,2-a>pyridine(123730-03-0)
• EPA Substance Registry System: 7-methyl-2-(2'-nitrophenyl)imidazo<1,2-a>pyridine(123730-03-0)

Safety Data

• Hazardous Substances Data: 123730-03-0(Hazardous Substances Data)

Upstream product

• 695-34-1 2-Amino-4-methylpyridine 
• 253684-24-1 1-(2,2-dibromovinyl)-2-nitrobenzene 
• 552-89-6 2-nitro-benzaldehyde 
• 6851-99-6 2-bromo-1-(2-nitrophenyl)ethanone 

Downstream Products

• 1621431-74-0 10-methyl-6-phenylpyrido[2',1':2,3]imidazo[4,5-c]quinoline 
• 1621431-75-1 6-(4-nitrophenyl)-9-methyl-5,6b,11-triaza-benzo[a]fluorene 
• 1621431-76-2 6-(2-nitrophenyl)-9-methyl-5,6b,11-triaza-benzo[a]fluorene 
• 1621431-77-3 6-(3-nitrophenyl)-9-methyl-5,6b,11-triaza-benzo[a]fluorene 
• 1621431-78-4 6-(4-cyanophenyl)-9-methyl-5,6b,11-triaza-benzo[a]fluorene 
• 1621431-79-5 6-(4-isopropylphenyl)-9-methyl-5,6b,11-triaza-benzo[a]fluorene 
• 1621431-80-8 6-(4-bromophenyl)-9-methyl-5,6b,11-triaza-benzo[a]fluorene 
• 1621431-81-9 6-(4-N,N-dimethylaminophenyl)-9-methyl-5,6b,11-triaza-benzo[a]fluorene 
• 1621431-82-0 6-(4-methoxyphenyl)-10-methylpyrido[2',1':2,3]imidazo[4,5-c]quinoline 
• 1621431-83-1 4-(9-methyl-5,6b,11-triaza-benzo[a]fluoren-6-yl)phenol 
• 1621431-84-2 10-methyl-6-(3,4,5-trimethoxyphenyl)pyrido[2',1':2,3]imidazo[4,5-c]quinoline 
• 1621431-85-3 6-(4-fluorophenyl)-10-methylpyrido[2',1':2,3]imidazo[4,5-c]quinoline 
• 1621431-89-7 6,10-dimethyl-6-phenyl-5,6-dihydropyrido[2',1':2,3]imidazo[4,5-c]quinoline 
• 123730-04-1 3-formyl-7-methyl-2-(2'-nitrophenyl)imidazo<1,2-a>pyridine 

Relevant articles and documents

An expeditious microwave assisted one-pot sequential route to pyrido fused imidazo[4,5-c] quinolines in green media

An expeditious microwave assisted one-pot sequential route to synthesize pyrido fused imidazo[4,5-c]quinolinesviathe Pictet-Spengler cyclization strategy has been developed. In this study, substituted 2-amino pyridines are condensed with 2-bromo-2′-nitroa

Synthesis of biologically active pyridoimidazole/imidazobenzothiazole annulated polyheterocycles using cyanuric chloride in water

An efficient and mild protocol for rapid access to N-fused polyheterocycles via Pictet-Spengler type 6-endo cyclization using cyanuric chloride in an aqueous reaction medium has been developed. The protocol was successfully applied to a wide range of compounds including aryl/heteroaryl aldehydes (8a-o), ketones (10a-e), an electron-rich metallocene aldehyde (8e) and indoline-2,3-diones (12a-c) using cyanuric chloride (15-20 mol%) with tetra-n-butylammonium bromide (TBAB) (2.0 eq.) as an additive at 80-90 °C to give a good to excellent yield (66-92%) of polyheterocycles. Some of the synthesized compounds were found to exhibit antiplasmodial activity against chloroquine-sensitive (CQ-S) 3D7 and chloroquine-resistant (CQ-R) K1 strains of Plasmodium falciparum. This journal is the Partner Organisations 2014.