123732-04-7Relevant articles and documents
Quinolines by three-component reaction: Synthesis and photophysical studies
Sales, Eric S.,Schneider, Juliana M. F. M.,Santos, Marcos J. L.,Bortoluzzi, Adailton J.,Cardoso, Daniel R.,Santos, Willy G.,Merlo, Aloir A.
, p. 562 - 571 (2015)
The synthesis of five quinolines 8-octyloxy-4-[4-(octyloxy)phenyl]quinoline and 6-alkoxy- 2-(4-alkoxyphenyl)-4-[(4-octyloxy)aryl]quinolines are described by three-component coupling reaction mediated by Lewis acid FeCl3 and Yb(OTf)3. 4-n-octyloxybenzaldehyde, anisaldehyde, 4-n-octyloxyaniline p-anisidine, and 1-ethynyl-4-heptyloxybenzene, 1-ethynyl-4-octyloxybenzene and 2-ethynyl-6-heptyloxynaphthalene are the reagents in this protocol. A Yb3+ catalyst resulted in higher yields of quinolines than Fe3+. Polarizing optical microscopy (POM) revealed that none of the quinolines were liquid crystals, even the more anisotropic. UV-Vis measurements of one of the quinolines in polar solvent show two absorption bands at 280 and 350 nm related to π,π?and n,π?transitions. No changes were observed to lower-energy absorption band (ε 4 mol L-1 cm-1) related to n,π?transition. A laser flash photolysis study for one of the quinolines relates a main transient band at 450 nm with a lifetime of 2.6 μs in ethanol, which is completely quenched in the presence of oxygen. This transient band was assigned to triplet-triplet absorption of one of the quinolines, which is semi-oxidised in the presence of phenol. Radiative rate constants have been determined along singlet and triplet excited state energies (3.39 and 3.10 eV, respectively). The chemical structure of one of the quinolines was also unequivocally confirmed by single-crystal X-ray analysis.
FUSED PYRIMIDINE COMPOUNDS AS KCC2
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Page/Page column 43-44, (2021/09/17)
The invention concerns compounds of Formula (I): (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R7 and ring A have any of the meanings hereinbefore defined in the description; process for their preparation; pharmaceutical compositions containing them and their use in treating KCC2 mediated diseases.
Synthesis and Characterization of a New Series of Paramagnetic Ferroelectric Liquid Crystalline Nitroxide Radicals
Uchida, Yoshiaki,Tamura, Rui,Suzuki, Katsuaki,Takahashi, Hiroki,Aoki, Yoshio,Nohira, Hiroyuki
, p. 89 - 106 (2015/09/01)
A new series of all-organic liquid-crystalline (LC) chiral radical compounds,trans-1-alkoxyphenyl-4-[(4-(4-alkoxyphenyl)-2,5-dimethylpyrrolidine-1-oxy-2-yl)-benzylideneamino]benzenes (1) with various alkyl chains, containing a chiral nitroxide unit in the mesogen core were synthesized and their LC properties were fully characterized. The enantiomerically enriched compounds (2S,5S)-1 showed N, TGBA, SmA and SmC phases, while the racemates (±)-1 exhibited N, SmA and SmC phases. The phase transition behavior and the ferroelectric properties of the SmC phase of (2S,5S)-1 differed from those of previously reported analogues with an ester group as a substitute for the imino group of (2S,5S)-1. Some of the (2S,5S)-1 series showed a temperature-dependent spontaneous polarization PS (θ) inversion. We discuss the origin of this difference in terms of their molecular structures optimized by molecular orbital calculations. The phase transition behavior supports the hypothesis that the large φ, which is defined as the angle between the molecular long axis (one of the principal axes of inertia) and the direction of the dipole moment in each molecule, results in the stabilization of the SmA (SmA) phase.
CYCLOHEXADIENE FULLERENE DERIVATIVES
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Page/Page column 78; 79; 87, (2015/03/28)
The invention relates to novel fullerene derivatives, to methods for their preparation and educts or intermediates used therein, to mixtures and formulations containing them, to the use of the fullerene derivatives, mixtures and formulations as organic semiconductors in, or for the preparation of, organic electronic (OE) devices, especially organic photovoltaic (OPV) devices and organic photodetectors (OPD), and to OE, OPV and OPD devices comprising, or being prepared from, these fullerene derivatives, mixtures or formulations.
Microwave mediated protection of hindered phenols and alcohols
Pothi, Tejas,Dawange, Mahesh,Chavan, Kamlesh,Sharma, Rajiv,Deka, Nabajyoti
, p. 706 - 711 (2013/03/28)
Hindered phenols and alcohols were protected as their corresponding ethers using different alkylating agents in presence of KOH/DMSO under microwave irradiation.
Synthesis of 1,4-bis[2,2-bis(4-alkoxyphenyl)vinyl]benzenes and side chain modulation of their solid-state emission
An, Peng,Shi, Zi-Fa,Dou, Wei,Cao, Xiao-Ping,Zhang, Hao-Li
supporting information; experimental part, p. 4364 - 4367 (2010/11/17)
Figure Presented. A series of 1,4-bis[2,2-bis(4-alkoxyphenyl)vinyl]benzene molecules with aggregation-induced emission (AIE) activity were synthesized. The conformations and packing arrangements of these molecules in the solid state can be adjusted by changing the side chains, which subsequently modulates their solid-state emission. The fluorescence quantum yield of 1e with the n-C 6H13 side chain in the solid state could reach up to 60.3% in the solid state.
Buchwald protocol applied to the synthesis of N-heterotolan liquid crystals
Vasconcelos, Ursula B.,Schrader, Abel,Vilela, Guilherme D.,Borges, Antonio C.A.,Merlo, Aloir A.
, p. 4619 - 4626 (2008/09/20)
A homologous series of the new N-heterotolans 8a-d were synthesized using two cross-coupling reactions mediated by copper and palladium/copper. The final compounds present the phenyl-pyridyl framework connected by the acetylene group. The evaluation of th
Unprecedented Negishi coupling at C-Br in the presence of a stannyl group as a convenient approach to pyridinylstannanes and their application in liquid crystal synthesis
Getmanenko, Yulia A.,Twieg, Robert J.
, p. 830 - 839 (2008/09/18)
(Chemical Equation Presented) The 2-bromo-5(or 6)-tri-n- butylstannylpyridines, prepared from dibromopyridines and i-PrMgCl at room temperature, undergo Negishi coupling with either alkyl or arylzinc chlorides. The new alkyl- and aryl-substituted pyridylstannanes produced are shown to be suitable for further functionalization by Stille coupling. A group of new liquid crystalline materials with aromatic cores comprised of pyridine and thiophene rings were prepared utilizing these new pyridinylstannanes as key intermediates.
Direct visual detection of the stereoselectivity of a catalytic reaction
Eelkema, Rienk,Van Delden, Richard A.,Feringa, Ben L.
, p. 5013 - 5016 (2007/10/03)
Color vision: The enantiomeric excess of the products of an enantioselective catalytic reaction can be determined by a liquid-crystal-based color test. After a simple workup, doping of the reaction product into a liquid crystal affords brightly colored LC