29147-88-4

Basic information

• Product Name: 4-N-HEPTYLOXYBENZONITRILE
• Synonyms: P-(HEPTYLOXY)BENZONITRILE;4-N-HEPTYLOXYBENZONITRILE;4-HEPTYLOXYBENZONITRILE
• CAS NO: 29147-88-4
• Molecular Formula: C₁₄H₁₉NO
• Molecular Weight: 217.31
• Product Categories: Aromatic Nitriles;Nitrile;Anisoles, Alkyloxy Compounds & Phenylacetates;Nitriles
• Mol File: 29147-88-4.mol

Chemical Properties

• Boiling Point: 341.3 °C at 760 mmHg
• Flash Point: 144.1 °C
• Appearance: /
• Density: 0.98 g/cm³
• Vapor Pressure: 8.1E-05mmHg at 25°C
• Refractive Index: 1.504
• CAS DataBase Reference: 4-N-HEPTYLOXYBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-N-HEPTYLOXYBENZONITRILE(29147-88-4)
• EPA Substance Registry System: 4-N-HEPTYLOXYBENZONITRILE(29147-88-4)

Safety Data

• Hazardous Substances Data: 29147-88-4(Hazardous Substances Data)

Usage

Uses

Used in Research and Industry:
4-N-Heptyloxybenzonitrile is used as a chemical intermediate for the synthesis of other organic compounds, playing a crucial role in the development of new chemical entities and materials.
Used in Pharmaceutical Development:
4-N-Heptyloxybenzonitrile is used as a building block in the creation of more complex molecules, particularly in the development of pharmaceuticals and other bioactive compounds, due to its versatile chemical structure and potential for further functionalization.
Used in Chemical Reactions:
4-N-Heptyloxybenzonitrile is utilized as a reagent in various chemical reactions, facilitating the formation of desired products and contributing to the advancement of synthetic chemistry.

InChI:InChI=1/C14H19NO/c1-2-3-4-5-6-11-16-14-9-7-13(12-15)8-10-14/h7-10H,2-6,11H2,1H3

Upstream product

• 629-04-9 1-Bromoheptane 
• 767-00-0 4-cyanophenol 
• 111-70-6 n-heptan1ol 
• 557-21-1 zinc(II) cyanide 
• 123732-04-7 4-n-heptyloxybromobenzene 

Downstream Products

• 1443791-80-7 (Z)-4-(heptyloxy)-N’-hydroxybenzimidamide 
• 1443788-24-6 (S)-2-(4-(tert-butyl)benzamido)-3-(4-(3-(4-(heptyloxy)phenyl)-1,2,4-oxadiazol-5-yl)phenyl)propanoic acid 
• 1443791-84-1 (S)-methyl 2-(4-(tert-butyl)benzamido)-3-(4-(((4-(heptyloxy)benzimidamido)oxy)carbonyl)phenyl)propanoate 
• 1443791-83-0 (S)-methyl 2-(4-(tert-butyl)benzamido)-3-(4-(3-(4-(heptyloxy)phenyl)-1,2,4-oxadiazol-5-yl)phenyl)propanoate 
• 1443792-00-4 (S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(2-(4-(heptyloxy)phenyl)thiazol-4-yl)phenyl)propanoate 
• 1443791-99-8 4-(4-bromophenyl)-2-(4-(heptyloxy)phenyl)thiazole 
• 77477-92-0 4-(heptyloxy)benzothioamide 
• 147080-46-4 4-Heptyloxy-N-hydroxy-benzamidine 

Relevant articles and documents

Pyrrolopyrrole aza boron dipyrromethene based two-photon fluorescent probes for subcellular imaging

A series of pyrrolopyrrole aza boron dipyrromethene derivatives have been designed and synthesised as two-photon fluorescent probes. The bisalkynyl analogues, having a donor-π-donor quadrupolar skeleton, show a red-shifted Q band at ca. 700 nm in toluene and a two-photon absorption (TPA) cross-section up to 2349 GM at 1040 nm. To enable these dyes to be used for subcellular imaging, a branched oligoethylene glycol unit has been introduced to enhance their hydrophilicity and biocompatibility, and a potential organelle-selective group, namely triphenylphosphonium or morpholine moiety has also been added with a view to targeting the mitochondria or lysosomes respectively. The resulting conjugates are essentially non-aggregated in deionised water, exhibiting an intense Q band at 668 nm and a TPA cross-section up to 384 GM at 1040 nm. These spectral features have been analysed using density functional theory calculations, which suggest that the TPA is mainly due to the S0 → S2 transition. In the subcellular imaging study, it has been found that the triphenylphosphonium-containing derivative can localise in the lysosomes of HeLa human cervical carcinoma cells, which may be a result of its positive charge and the negative logP value (-2.46, P = partition coefficient), while the morpholine-substituted analogue does not exhibit preferential subcellular localisation.

GLP-1 RECEPTOR MODULATORS

Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where "^^^^" represents either or both the R and S form of the compound) (I) where A, B, C, Y1, Y2, Z, R1, R2, R3, R4, R5, W1, n, p and q are as defined herein.

NOVEL GLP-1 RECEPTOR MODULATORS

Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where "()" represents either or both the R and S form of the compound): where A, B, C, Y1, Y2, Z, R1, R2, R3, R4, R5, W1, n, p and q are as defined herein.

NOVEL GLP-1 RECEPTOR MODULATORS

The invention relates to compounds that modulate the glucagon-like peptide 1 (GLP-1) receptor, methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds are act as modulators or potentiators of GLP-1 receptor on their own, or with receptor ligands including GLP-1 peptides GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where"﹋" represents either or both the R and S form of the compound): where A, B, C, Y1, Y2, Z, R1, R2, R3, R4, R5, W1, n, p and q are as defined herein.

Polymer-bound triphenylphosphine as traceless reagent for Mitsunobu reactions in combinatorial chemistry: Synthesis of aryl ethers from phenols nad alcohols

The synthesis of aryl ethers from phenols and alcohols using polymer- bound triphenylphosphine and diethyl azodicarboxylate (DEAD) is described. The polymer-bound triphenylphosphines are easily removed by filtration from the reaction products. This method

The Synthesis and Liquid Crystal Properties of Some Series Homologues of 1,2,4-Oxadiazole Derivatives

Homologues series of some derivatives of 3,5-(4-substituted phenyl)-1,2,4-oxydiazole were synthesized and their phase behavior studied.Introduction of the pentagonal heteroaromatic ring leads to significant changes in mesomorphic behavior in comparison with analogous compounds containing the phenyl ring.The synthesised compounds exhibit smectic and nematic phases. - Keywords: 1,2,4-oxadiazole, nematic and smectic liquid crystals