123749-03-1

Basic information

• Product Name: (5aR,8aR,SS)-1H-2,3,5,5a,6,7,8,8a-octahydro-9-<(4-methylphenyl)sulfinyl>-5-oxocyclopentindolizine
• CAS NO: 123749-03-1
• Molecular Weight: 315.436
• Mol File: 123749-03-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5aR,8aR,SS)-1H-2,3,5,5a,6,7,8,8a-octahydro-9-<(4-methylphenyl)sulfinyl>-5-oxocyclopentindolizine(CAS DataBase Reference)
• NIST Chemistry Reference: (5aR,8aR,SS)-1H-2,3,5,5a,6,7,8,8a-octahydro-9-<(4-methylphenyl)sulfinyl>-5-oxocyclopentindolizine(123749-03-1)
• EPA Substance Registry System: (5aR,8aR,SS)-1H-2,3,5,5a,6,7,8,8a-octahydro-9-<(4-methylphenyl)sulfinyl>-5-oxocyclopentindolizine(123749-03-1)

Safety Data

• Hazardous Substances Data: 123749-03-1(Hazardous Substances Data)

Upstream product

• 872-32-2 2-methyl-1H-pyrroline 
• 1517-82-4 (1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate 
• 1519-39-7 (R)-methyl p-tolyl sulfoxide 
• 10267-94-4 ethyl cyclopent-1-enecarboxylate 
• 123642-79-5 (+)-(R)-4,5-dihydro-2-<<(4-methylphenyl)sulfinyl>methyl>-3H-pyrrole 

Relevant articles and documents

Stereoselective Additions of Chiral α-Sulfinyl Ketimine Anions to Ene Esters. Asymmetric Syntheses of Indoloquinolizidine and Yohimban Alkaloids

The in-situ 1,4-addition/ring-closure reactions of chiral α-sulfinyl ketimine anions with acyclic and cyclic ene esters offer a simple, convenient route for the construction of chiral cyclic alkaloids having a nitrogen-atom ring juncture.Asymmetric induction in the conjugate-addition reaction of the carbanions derived from α-sulfinyl ketimines possessing chiral sulfur with various cyclic and acyclic ene esters, subsequent ring-closure reaction, and reduction of the resulting β-sulfinyl enamides were utilized in the syntheses of (-)-1,2,3,4,6,7,12,12b-octahydroindoloquinolizine , (-)-alloyohimban , (+)-3-epi-alloyohimban , and (-)-yohimban .