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DODECACARBONYLTETRA-MU-HYDRIDOTETRAOSMIUM, also known as Os4(CO)12(H)4, is a chemical compound that features a cluster of four osmium atoms surrounded by twelve carbonyl groups and four hydride atoms. This cage-like structure endows it with high reactivity, making it a valuable catalyst in various chemical reactions.

12375-04-1

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12375-04-1 Usage

Uses

Used in Organic Synthesis:
DODECACARBONYLTETRA-MU-HYDRIDOTETRAOSMIUM is used as a catalyst for the hydrogenation of alkenes and alkynes, which is crucial in the production of various organic compounds.
Used in Specialty Chemicals Production:
In the specialty chemicals industry, DODECACARBONYLTETRA-MU-HYDRIDOTETRAOSMIUM is used as a catalyst to facilitate specific chemical reactions, contributing to the synthesis of unique and high-value products.
Used in Pharmaceutical Production:
DODECACARBONYLTETRA-MU-HYDRIDOTETRAOSMIUM is utilized as a catalyst in the synthesis of certain pharmaceuticals, playing a key role in the development of new drugs and medicines.

Check Digit Verification of cas no

The CAS Registry Mumber 12375-04-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,3,7 and 5 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 12375-04:
(7*1)+(6*2)+(5*3)+(4*7)+(3*5)+(2*0)+(1*4)=81
81 % 10 = 1
So 12375-04-1 is a valid CAS Registry Number.
InChI:InChI=1/12CO.4Os.4H/c12*1-2;;;;;;;;/r2C6H2O6Os2/c2*7-1-13(2-8,3-9)14(4-10,5-11)6-12/h2*13-14H

12375-04-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name carbon monoxide,osmium

1.2 Other means of identification

Product number -
Other names DODECACARBONYLTETRA-M-HYDRIDOTETRA OSMIUM

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:12375-04-1 SDS

12375-04-1Downstream Products

12375-04-1Relevant academic research and scientific papers

Methylidyne-alkyne coupling on triruthenium clusters and hydrogenation of cluster-bound 1,3-dimetalloallyl units. A new model for Fischer-Tropsch chain growth

Beanan, Lawrence R.,Keister, Jerome B.

, p. 1713 - 1721 (2008/10/08)

Alkylidyne-alkyne coupling occurs upon reaction of H3Ru3(μ3-CX)(CO)9 (X = OMe, Me, Ph, or CH2CH2CMe3) at 25 °C or HRu3(μ-CX)(CO)10 (X = OMe) at 60 °C with alkynes R1C2R2, forming 1,3-dimetalloallyl clusters HRu3(μ3-η3-XCCRCR)(CO)9 (X = OMe, (R1, R2) = (H, H), (Me, Me), (Ph, Ph), (H, Ph), (H, CMe3), (H, n-Bu), (H, CO2Me), (Ph, CO2Me), (H, OEt); X = Ph, (R1, R2) = (Ph, Ph); X = Me, (R1, R2) = (Me, Me); X = CH2CH2CMe3, (R1, R2) = (Ph, Ph)) in yields of 15-90%. In an analogous fashion, HOs3(μ-COMe)(CO)10 and PhC2Ph yield HOs3(μ3-η3-MeOCCPhCPh)(CO)9. One equivalent of the appropriate cis-alkene is formed from reduction of alkyne by H3Ru3(μ3-CX)(CO)9. With unsymmetrical alkynes the relative amounts of the two possible regioisomers depend upon the alkyne substituents. Coupling from either H3R3(μ3-COMe)(CO)9 or HRu3(μ-COMe)(CO)10 forms HRu3(μ3-η3-MeOCCR1CR 2)(CO)9 in the relative amounts (R1, R2) = (H, Ph)/(Ph, H), 3:1, (H, n-Bu)/(n-Bu, H), 2:1, (H, CMe3,)/(CMe3, H), 20:1, (H, CO2Me)/(CO2Me, H), 2:1, (H, OEt)/(OEt, H), 1:0, (Me, C7-H15, Me), 3:1, and (CO2Me, Ph)/(Ph, CO2Me), 2:1. Hydrogenation (90 °C, 1-4 atm) of HRu3(μ3-η3MeOCCR1CR 2)(CO)9 ((R1, R2) = (H, H), (H, CMe3), (Me, Me), (Ph, Ph), (H, OEt), (H, Ph), (H, n-Bu), (n-Bu, H), (H, CO2Me)) produces in each case the corresponding H3Ru3(μ3CCHR1CH2R 2)(CO)9 in yields of 6-43%; also formed are substantial quantities of H4Ru4(CO)12. Hydrogenation of DRu3(μ3-η3-MeOCCHCCMe 3)(CO)9 produces exclusively H3Ru3(μ3-CCH2CHDCMe 3)(CO)9. This alkylidyne-alkyne coupling and subsequent hydrogenation to form an alkylidyne of longer carbon chain length suggests a mechanism to account for 2-methylated hydrocarbon products in the Fischer-Tropsch reaction.

SYNTHESIS OF HYDRIDOTRIOSMIUM COMPLEXES CONTAINING ISOMERIC μ-CARBOXAMIDO, , AND μ-IMINYL, , GROUPS. CRYSTAL AND MOLECULAR STRUCTURE OF Os3(CO)10, R' = C(=O)NHCH3

Lin, Ying-Chih,Mayr, Andreas,Knobler, Carolyn B.,Kaesz, Herbert D.

, p. 207 - 230 (2007/10/02)

Primary or secondary aliphatic amines are observed to react with Os3(CO)12 in excess amine or other polar solvents at temperatures in the range -10 to 25 deg C.One mole of CO is evolved and a μ(O,C)-carboxamido complex (1) is isolated in high yield: Os3(CO)10 (1a, R = Me, R' = H; 1b, R = R' = Me; 1c, R = n-Pr, R' = H, 1d, R = n-Bu, R' = H; 1e, R = Et, R' = H).The 1H NMR spectrum of 1e indicates the existence of two isomers due to the restricted rotation around the C-N bond of the μ-carboxamido group.Reaction of methyl or ethyl isocyanate with Os32(CO)10 at room temperature under N2 gives three principal products: a μ(O,N)-formamido complex, Os3(CO)10 (2), the μ(O,C)-carboxamido complex, 1, and a μ(C,N)-iminylurethane complex, Os3(CO)10, (4, R' = C(=O)NHR).Product 1 in this reaction arises from isomerization of an intermediate μ(C,N)-hydroxyiminyl complex, Os3(μ-H,μ-C(OH)=NR(CO)10 (3).This complex is isolated upon initial chromatography of the reaction mixture.For the isomerization of 3 to 1, t1/2 17.5 d in CDCl3 solution, Ea 92 kJ/mol.Spectroscopic data indicate that 3 is a mixture of tautomers in ratio of 19/1 in CDCl3: Os3(CO)10 (3-enol) and Os3(CO)10 (3-keto). The structure of 4 has been determined at -158 deg C using a Syntex P computer-automated diffractometer and graphite-monochromatized Mo-Kα radiation.Some 2936 unique reflections with I >3?(I) were used in the refinement to give final discrepancy indices of R = 0.030 and Rw = 0.037.The complex crystallizes in the monoclinic space group P21/c in a cell having the dimensions of a 13.413(3) Angstroem, b 16.712(3) Angstroem, c 9.400(3) Angstroem, and β 95.01(2) deg.The calculated density is 3.06 g cm-3.

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