123760-77-0Relevant academic research and scientific papers
A Phenylalanine Derivative Containing a 4-Pyridine Group Can Construct Both Single Crystals and a Selective Cu-Ag Bimetallohydrogel
Wei, Chuan-Wan,Wang, Xiao-Juan,Gao, Shu-Qin,Wen, Ge-Bo,Lin, Ying-Wu
, p. 1349 - 1353 (2019)
Metallohydrogels are attractive biomaterials, whereas formation of a selective bimetallogel in aqueous solution has rarely been explored. In this study, we show that a phenylalanine derivative containing a 4-pyridine group can not only assemble to form si
A Chiral Ligand Assembly That Confers One-Electron O2 Reduction Activity for a Cu2+-Selective Metallohydrogel
Wang, Xiaojuan,Wei, Chuanwan,Su, Ji-Hu,He, Bo,Wen, Ge-Bo,Lin, Ying-Wu,Zhang, Yi
, p. 3504 - 3508 (2018)
The design of functional metallohydrogels is attractive but challenging. A rational approach is introduced for designing functional metallohydrogels using chiral ligands, a phenylalanine derivative with a pyridyl group (l/d-PF). Intriguingly, the as-prepared metallohydrogel exhibits excellent O2 binding and activating properties. Insights into the O2 binding pathway reveals the presence of a novel [(l+d)-PF-Cu3+-O2?] species, which can efficiently reduce ferric cytochrome c with the reactive O2? by receiving an electron from reductant ascorbic acid. This study provides helpful instructions for developing new artificial systems with specific functions through the effective combination of chiral ligands with metal ions.
Designing isometrical gel precursors to identify the gelation pathway for nickel-selective metallohydrogels
Wang, Xiaojuan,He, Ting,Yang, Lan,Wu, Huiqiong,Yin, Jiafu,Shen, Rujuan,Xiang, Juan,Zhang, Yi,Wei, Chuanwan
, p. 18438 - 18442 (2016/12/03)
Two novel multi-responsive metallohydrogels, namely, 2-PF-Ni and 3-PF-Ni, were successfully constructed from phenylalanine derivatives. The 2-PF gelator shows specific responses to Ni2+; particularly, 2-PF-Ni is lavender colored, which has been rarely reported among hydrogels triggered by Ni2+. 3-PF-Ni is light green and exhibits perfect thixotropy. This paper provides insights into the gelation mechanisms of these two metallogels.
N-SUBSTITUTED AMINO ACID DERIVATIVES WITH HYPERALPHALIPOPROTEINAEMIC ACTIVITY
Baggaley, Keith H.,Fears, Robin,Ferres, Harry,Geen, Graham R.,Hatton, Ian K.,et al.
, p. 523 - 532 (2007/10/02)
A series of N-substituted amino acid derivatives was synthesized and the compounds were evaluated for their effects on serum total cholesterol, HDL cholesterol and triglycerides in experimental animals.Hyperalphalipoproteinaemic activity was found for some of these compounds tested, especially BRL 26314 (2) and related 3-aryl-2-aminopropionic acids.Structure-activity relationships are discussed.Keywords: N-substituted amino acid derivatives / hyperalphalipoproteinaemic activity
