123771-19-7Relevant academic research and scientific papers
Synthesis of 3-(Dibromoacetyl)tropolone and its Reactions with Thioureas and Thioamides
Maeda, Yasunari,Imafuku, Kimiaki
, p. 349 - 352 (2007/10/02)
3-(Dibromoacetyl)tropolone (3) was obtained in the reaction of 3-acetyltropolone with two equimolar amounts of phenyltrimethylammonium tribromide.This tropolone 3 reacted with thiourea, 1-methyl-2-thiourea, and 1-phenyl-2-thiourea to afford N-unsubstituted and N-methyl- or N-phenyl-substituted 3-(2-amino-4-thiazolyl)tropolones.The reactions of 3 with thioacetamide and thiobenzamide gave 3-(2-methyl- and 2-phenyl-4-thiazolyl)tropolones.
Hantzsch Reaction of 3-(2-Bromoacetyl)tropolone. Synthesis of 3-(4-Thiazolyl)tropolones
Qian, Chang-Yi,Jin, Zhong-Tian,Yin, Bing-Zhu,Imafuku, Kimiaki
, p. 601 - 604 (2007/10/02)
3-Acetyltropolone was brominated with phenyltrimethylammonium tribromide to afford 3-(2-bromoacetyl)tropolone (2), whose reactions with thiourea, thioformamide, and ammonium dithiocarbamate gave respectively 3-(2-amino-4-thiazolyl)-, 3-(4-thiazolyl)-, and 3-(2-mercapto-4-thiazolyl)tropolone.In a similar manner, compound 2 was treated with six 1-substituted 2-thioureas and three thioamides to give the corresponding 3-(4-thiazolyl)tropolone derivatives.
