123790-92-1

Upstream product

• 3840-88-8 6,6'-dimethyl-2,2'-dibromo-1,1'-biphenyl 
• 15873-72-0 dicyclohexylphosphinoyl chloride 
• 570-24-1 2-Methyl-6-nitroaniline 
• 55153-02-1 2,2'-dinitro-6,6'-dimethyl-1,1'-biphenyl 
• 95-53-4 o-toluidine 
• 123790-92-1 2,2'-bis(dicyclohexylphosphine dioxide)-6,6'-dimethyl-1,1'-biphenyl 
• 86560-87-4 2,2'-diamino-6,6'-dimethylbiphenyl 
• 6277-17-4 2-iodo-3-nitrotoluene 
• 120-66-1 N-(2-methylphenyl)acetamide 
• 478920-41-1 carbon dioxide-methanol 

Downstream Products

• 123790-92-1 (R)-(-)-2,2'-bis(dicyclohexylphosphine dioxide)-6,6'-dimethyl-1,1'-biphenyl 
• 123790-92-1 (S)-(+)-2,2'-bis(dicyclohexylphosphine dioxide)-6,6'-dimethyl-1,1'-biphenyl 
• 123790-90-9 (R)-(-)-2,2'-bis(dicyclohexylphosphino)-6,6'-dimethyl-1,1'-biphenyl 
• 123790-90-9 (S)-(+)-2,2'-bis(dicyclohexylphosphino)-6,6'-dimethyl-1,1'-biphenyl 

Relevant academic research and scientific papers

Ruthenium-optically active phosphine complex

A ruthenium-optically active phosphine complex having, as a ligand, BICHEP which means 2,2'-bis(dicyclohexylphosphino)-6,6'-dimethyl-1,1'-biphenyl represented by formula (I): STR1 is disclosed, which can catalyze asymmetric syntheses, such as asymmetric hydrogenation, asymmetric isomerization, and asymmetric silylation, exhibiting excellent catalytic activity and providing high optical purity.

Synthesis of Atropisomeric 2,2'-Bis(dicyclohexylphosphino)-6,6'-dimethyl-1,1'-biphenyl (BICHEP) and Its Use in Rh(I)-catalyzed Asymmetric Hydrogenation of Prochiral Olefins

The atropisomeric bis(dialkylarylphosphine) ligands, (R)-(-)- and (S)-(+)-2,2'-bis(dicyclohexylphosphino)-6,6'-dimethyl-1,1'-biphenyl (BICHEP) (1) have been newly synthesized, whose Rh(I) complexes are highly efficient catalysts for asymmetric hydrogenations of ethyl α-(benzamido)cinnamate and dimethyl itaconate in up to 98percent yields and 98-99percent enantiomeric excess.