123797-50-2Relevant academic research and scientific papers
Reaction of 4,6-dimethoxy-3-methylindole with aromatic aldehydes: A simple synthesis of calix[3]indoles
Black, David St.C.,Craig, Donald C.,Kumar, Naresh
, p. 311 - 318 (2007/10/03)
2,7:2,7:2,7-Linked calix[3]indoles (3a-d) have been prepared by the reaction of 4,6-dimethoxy-3-methylindole (1) and benzaldehydes with phosphoryl chloride or by a direct reaction of di(4,6-dimethoxy-3-methylindol-2-yl)phenylmethanes (2a-d) with phosphoryl chloride. An X-ray crystal structure determination of the macrocycle (3d) is reported. 4,6-Dimethoxy-3-methylindolemethanols (9) and (10) were prepared and reacted with phosphoryl chloride to study the mechanism of formation of the macrocycle.
Synthesis of a New Class of Indole-containing Macrocycles
Black, David St. C.,Craig, Donald C.,Kumar, Naresh
, p. 425 - 426 (2007/10/02)
4,6-Dimethoxy-3-methylindole can be converted by treatment with aryl aldehydes and phosphoryl chloride in chloroform into macrocyclic tri-indolyl methanes, with the indole rings linked at C-2 and C-7.
