123801-78-5

Basic information

• Product Name: L-N-[(2R)-2-(1-naphthylmethyl)-3-p-toluenesulfonyloxypropionyl]norleucine tert-butyl ester
• Synonyms: L-N-[(2R)-2-(1-naphthylmethyl)-3-p-toluenesulfonyloxypropionyl]norleucine tert-butyl ester
• CAS NO: 123801-78-5
• Molecular Weight: 553.72
• Mol File: 123801-78-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: L-N-[(2R)-2-(1-naphthylmethyl)-3-p-toluenesulfonyloxypropionyl]norleucine tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-N-[(2R)-2-(1-naphthylmethyl)-3-p-toluenesulfonyloxypropionyl]norleucine tert-butyl ester(123801-78-5)
• EPA Substance Registry System: L-N-[(2R)-2-(1-naphthylmethyl)-3-p-toluenesulfonyloxypropionyl]norleucine tert-butyl ester(123801-78-5)

Safety Data

• Hazardous Substances Data: 123801-78-5(Hazardous Substances Data)

Upstream product

• 123802-68-6 (2R)-3-benzyloxy-2-(1-naphthylmethyl)propionic acid 
• 3243-42-3 1-Naphthalenepropanoic acid 
• 3163-27-7 2-(bromomethyl)naphthalene 
• 123833-67-0 (S)-2-(2-Ethoxycarbonyl-3-naphthalen-1-yl-propionylamino)-hexanoic acid tert-butyl ester 
• 123802-60-8 (2R)-3-hydroxy-2-(1-naphthylmethyl)propionic acid 
• 129431-11-4 (4S)-3-<(2R)-3-Benzyloxymethyl-2-(1-naphthylmethyl)propionyl>-4-isopropyl-2-oxazolidinone 
• 119358-08-6 4-(S)-isopropyl-3-<3-(1-naphthyl)-1-oxopropyl>-2-oxazolidinone 
• 123801-76-3 L-N-[(2R)-3-hydroxy-2-(1-naphthylmethyl)-propionyl]norleucine tert-butyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 15911-73-6 L-norleucine tert-butyl ester 

Downstream Products

• 120716-81-6 (2S,3R,4S)-4--L-norleucyl>amino-5-cyclohexyl-1-morpholino-2,3-pentadienol 

Relevant articles and documents

N-substituted acylamino acid compounds, process for their production and their use

The present invention provides an N-substituted acylamino acid compound of the formula: STR1 a process for their production and pharmaceutical uses, and intermediates useful for their production.

A STEREOSPECIFIC SYNTHESIS OF A RENIN INHIBITOR (BW-175) WHICH INCORPORATES A SULFONEMETHYLENE ISOSTERE AND A DIHYDROXYETHYLENE ISOSTERE.

(2R,3R,4S)-4-norleucyl>amino-5-cyclohexyl-1-morpholino-2,3-pentanediol (BW-175) was synthesized stereospecifically.

Synthesis of a homostatine-containing renin inhibitor which incorporates a sulfonemethylene isostere at its N-terminus

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