123837-25-2

Upstream product

• 64133-02-4 α-(tetrahydropyranyloxy)benzyl cyanide 
• 38206-86-9 methyl quinuclidine-3-carboxylate 
• 123837-02-5 3-<3-<1-phenyl-1-(tetrahydropyranyloxy)methyl>-1,2,4-oxadiazol-5-yl>quinuclidine 
• 123837-01-4 α-(tetrahydropyranyloxy)phenylacetamide oxime 

Downstream Products

• 123836-90-8 3-<3-(1,1-diphenyl-1-hydroymethyl)-1,2,4-oxadiazol-5-yl>quinuclidine 
• 123836-99-7 3-(3-benzoyl-1,2,4-oxadiazol-5-yl)quinuclidine 

Relevant academic research and scientific papers

Squalene synthetase inhibitors

Compounds of structural formula (I): STR1 are squalene synthestase inhibitors useful in inhibiting the biosynthesis of cholesterol in the treatment of hypercholesterolemia and related disorders.

Novel Quinuclidine-Based Ligands for the Muscarinic Cholinergic Receptor

Recent clinical studies on Alzheimer's patients have implied that only agents displaying high efficacy at the cortical muscarinic receptor have yielded encouraging results.This paper describes the design, synthesis, and biochemical characterization of nov