123837-01-4Relevant academic research and scientific papers
1,3-DISUBSTITUTED HETEROARYL NMDA/NR2B ANTAGONISTS
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Page/Page column 56, (2010/10/20)
Compounds represented by Formula I: (wherein A, B, D, P, Q, R1, R2, R3, W and Y are described herein) or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological co
Novel Quinuclidine-Based Ligands for the Muscarinic Cholinergic Receptor
Saunders, John,Cassidy, Mark,Freedman, Stephen B.,Harley, Elizabeth A.,Iversen, Leslie L.,et al.
, p. 1128 - 1138 (2007/10/02)
Recent clinical studies on Alzheimer's patients have implied that only agents displaying high efficacy at the cortical muscarinic receptor have yielded encouraging results.This paper describes the design, synthesis, and biochemical characterization of nov
