1238625-89-2Relevant academic research and scientific papers
Efficient palladium-catalyzed Suzuki-Miyaura cross-coupling of iodoethynes with arylboronic acids under aerobic conditions
Tang, Jian-Sheng,Xie, Ye-Xiang,Wang, Zhi-Qiang,Li, Jin-Heng
experimental part, p. 2789 - 2795 (2011/10/18)
Ligand-free palladium-catalyzed Suzuki-Miyaura cross-coupling of iodoethynes with arylboronic acids under aerobic conditions has been developed. In the presence of palladium(II) acetate and cesium carbonate, a variety of iodoethynes underwent the Suzuki-M
Palladium-catalyzed cross-coupling of electron-poor terminal alkynes with arylboronic acids under ligand-free and aerobic conditions
Zhou, Ming-Bo,Wei, Wen-Ting,Xie, Ye-Xiang,Lei, Yong,Li, Jin-Heng
experimental part, p. 5635 - 5642 (2010/11/04)
Palladium-catalyzed cross-coupling reaction of terminal alkynes with arylboronic acids has been described. In the presence of Pd(OAc)2 and Ag2O, a variety of terminal alkynes, including electron-poor terminal alkynes, smoothly underwent the reaction with numerous boronic acids to afford the corresponding internal alkynes in moderate to good yields. Moreover, this methodology was applied to the synthesis of 1H-isochromenes and diynes. It is noteworthy that the reaction proceeds under ligand-free and relative lower loading Pd conditions, and the maximal TONs (turnover numbers) of the reaction are up to 720,000.
