123884-02-6

Basic information

• Product Name: 3'-O-(1,3-benzodithiol-2-yl)-5'-O-trityl-N³-benzoyl-thymidine
• Synonyms: 3'-O-(1,3-benzodithiol-2-yl)-5'-O-trityl-N³-benzoyl-thymidine
• CAS NO: 123884-02-6
• Molecular Weight: 740.901
• Mol File: 123884-02-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3'-O-(1,3-benzodithiol-2-yl)-5'-O-trityl-N³-benzoyl-thymidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-O-(1,3-benzodithiol-2-yl)-5'-O-trityl-N³-benzoyl-thymidine(123884-02-6)
• EPA Substance Registry System: 3'-O-(1,3-benzodithiol-2-yl)-5'-O-trityl-N³-benzoyl-thymidine(123884-02-6)

Safety Data

• Hazardous Substances Data: 123884-02-6(Hazardous Substances Data)

Upstream product

• 57842-27-0 1,3-benzodithiol-2-ylium tetrafluoroborate 
• 123884-03-7 5'-O-trityl 3-N-benzoylthymidine 

Downstream Products

• 3416-05-5 3'-Deoxythymidine 
• 108895-42-7 3'-O-methylthymidine 

Relevant articles and documents

Facile Synthesis of 3'-O-Methylthymidine and 3'-Deoxythymidine and Related Deoxygenated Thymidine Derivative: A New Method for Selective Deoxygenation of Secondary Hydroxy Groups

This paper deals with convenient synthesis of 3'-O-methylthymidine (2) and 3'-deoxythymidine (3), which involve Ag2O-promoted methylation and Barton-Robins reductive deoxygenation, respectively.New methods for the regioselective 3'- and 5'-deoxygenation of thymidine have also been developed.Namely, compound 3 was synthesized by the 3',5'-O-diacylation of thymidine with phenyl chlorothionoformate (PTCF) followed by the selective 3'-reduction with tributyltin hydride and successive alkaline hydrolysis. 5'-Deoxythymidine (18) was obtained by the 5'-selective acylation of thymidine with PTCF followed by reduction with tributyltin hydride.