3416-05-5 Usage
Uses
Different sources of media describe the Uses of 3416-05-5 differently. You can refer to the following data:
1. 3’-Deoxythymidine inhibits the ability of bacteriophage T7 to infect Escherichia coli by inhibiting phage DNA synthesis. Also, it is a precursor of DNA polymerase β inhibitor.
2. Research tool for antiviral and anticancer studies.
Purification Methods
3'-Deoxyuridine is recrystallised from Me2CO/MeOH and is dried in a vacuum. [Michelson & Todd J Chem Soc 816 1955.]
Check Digit Verification of cas no
The CAS Registry Mumber 3416-05-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,1 and 6 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 3416-05:
(6*3)+(5*4)+(4*1)+(3*6)+(2*0)+(1*5)=65
65 % 10 = 5
So 3416-05-5 is a valid CAS Registry Number.
3416-05-5Relevant articles and documents
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Wempen,I.,Fox,J.J.
, p. 1020 - 1025 (1969)
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NMR studies of pyrimidinic nucleosides derived from 2,3-dideoxy-d-ribose with inhibitory activity on LINE-1 mobility
Banuelos-Sanchez, Guillermo,Franco-Montalban, Francisco,Tamayo, Juan A.
, p. 118 - 125 (2019/11/28)
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Synthesis of C3′ modified nucleosides for selective generation of the C3′-deoxy-3′-thymidinyl radical: A proposed intermediate in LEE induced DNA damage
Audat, Suaad A. S.,Trzasko Love, Cherylann,Al-Oudat, Buthina A. S.,Bryant-Friedrich, Amanda C.
experimental part, p. 3829 - 3837 (2012/06/29)
DNA damage pathways induced by low-energy electrons (LEEs) are believed to involve the formation of 2-deoxyribose radicals. These radicals, formed at the C3′ and C5′ positions of nucleotides, are the result of cleavage of the C-O phosphodiester bond throu
