1239016-73-9Relevant academic research and scientific papers
One-pot oxidation and rearrangement of propargylamines and in situ pyrazole synthesis
Chen, Jinshan,Properzi, Roberta,Uccello, Daniel P.,Young, Jennifer A.,Dushin, Russell G.,Starr, Jeremy T.
, p. 4146 - 4149 (2014)
Reported here are procedures for a one-pot oxidation and rearrangement of propargylamines to synthesize enaminones, with supporting mechanistic studies. Also reported are the extended one-pot syntheses of pyrazoles, including celecoxib and various heterocyclic compounds.
Base catalyzed intramolecular cycloaddition of dialkyl(4-hydroxybutyn2-yl) [3-(p-tolyl)propyn- - 2-yl]ammonium chlorides and intramolecular recyclization of the products obtained
Chukhajian,Ayrapetyan,Chukhajian,Panosyan
experimental part, p. 151 - 157 (2011/08/07)
Dialkyl(4-hydroxybutyn-2-yl)[3-(p-tolyl)propyn-2-yl]ammonium chlorides undergo a diene synthesis type intramolecular cyclization in aqueous base medium to give 2,2-dialkyl-4-hydroxymethyl-6-methyl-benzo[f]isoindolinium chlorides. Under conditions of aqueo
